Table 3 Effect of DOX and APG on sperm parameters.

From: Apigetrin ameliorates doxorubicin prompted testicular damage: biochemical, spermatological and histological based study

Parameters

Groups

Control

DOX

DOX + APG

APG

Epididymal sperm count (million/mL)

25.68 ± 1.21

7.33 ± 0.53##

18.36 ± 0.77**

25.93 ± 1.33***

Motility (%)

81.97 ± 1.22

33.84 ± 0.93##

72.37 ± 1.01**

82.56 ± 1.66***

Dead sperms (%)

15.92 ± 0.93

75.78 ± 0.87##

34.24 ± 1.19**

14.89 ± 1.03***

Head abnormality (%)

2.74 ± 0.37

33.38 ± 1.20##

7.41 ± 0.73**

2.69 ± 0.38***

Mid sperm abnormality (%)

0.58 ± 0.08

13.37 ± 1.27##

2.63 ± 0.19**

0.55 ± 0.08***

Tail abnormality (%)

4.71 ± 0.53

23.12 ± 1.89##

9.88 ± 0.45**

4.69 ± 0.52***

Hypo- osmotic swelled sperm count (HOS) (%)

87.92 ± 2.28

25.35 ± 1.15##

71.63 ± 0.83**

89.08 ± 2.38***

  1. Values based on mean ± SEM values. Significant differences are displayed as ##P < 0.01 compared to control group; **P < 0.01 compared to DOX-administered group, ***P < 0.001 compared to control group.
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