Table 4 Effect of DOX and APG on testicular histopathology.

Interstitial spaces (μm)

6.55 ± 0.68

73.90 ± 1.85^###

19.48 ± 1.49^b**

6.52 ± 0.67***

Tunica propria (μm)

85.63 ± 1.19

15.40 ± 1.23^###

64.34 ± 1.52**

86.53 ± 1.62***

Seminiferous tubules diameter (μm)

372.44 ± 5.17

138.41 ± 5.12^###

241.06 ± 6.08**

375.21 ± 6.09***

Seminiferous tubule epithelial height (μm)

74.44 ± 1.97

28.46 ± 1.81^###

73.57 ± 1.84**

73.39 ± 2.59***

Tubular lumen (μm)

32.68 ± 0.97

97.51 ± 3.06^###

57.14 ± 1.57**

32.17 ± 0.33***

Spermatogonia (n)

65.59 ± 1.32

24.80 ± 0.76^###

54.35 ± 1.05**

66.33 ± 1.15***

Primary spermatocytes (n)

55.99 ± 1.83

19.56 ± 1.62^###

44.22 ± 1.87**

58.61 ± 2.74***

Secondary spermatocytes (n)

46.77 ± 2.55

15.74 ± 1.58^###

34.78 ± 1.74**

48.64 ± 3.18***

Spermatids (n)

63.73 ± 0.90

24.95 ± 1.84^###

37.3 ± 15.85**

64.55 ± 1.22***