Figure 3 | Scientific Reports

Figure 3

From: Microbiomic association between the saliva and salivary stone in patients with sialolithiasis

Figure 3

Correlation of the 21 genera between saliva and salivary stones. (A) Venn diagram of the genera showing the overall overlap between groups after obtaining 21 genera by Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC). Significant differences between saliva from healthy individuals and salivary stones were observed in 23 genera, and between saliva from patients and salivary stones in 24, genera. No genera showed a statistically significant difference in abundance between saliva samples from patients and from healthy individuals. (B) Correlation plots between saliva from patients and salivary stones for 21 genera. Positive and negative correlations are represented by blue and red, respectively. Significant correlations are represented by asterisks. (*P < 0.05, **P < 0.01, ***P < 0.001) (C) Box plot of Peptostreptococcus, Porphyromonas, and Pseudomonas representing the centered-log ratio-transformed abundance. A Wilcoxon rank-sum test was used to assess differences in alpha-diversity between groups (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001).

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