Figure 12
From: Structural investigation of Trypanosoma cruzi Akt-like kinase as drug target against Chagas disease
Docking studies with human Akt inhibitor capivasertib and HsAkt and TcAkt. Docking derived model of capivasertib bound to (a) HsAkt-K and (b) TcAkt-K. 2D representation of interacting residues within 4 Å of capivasertib of (c) HsAkt-K and (d) TcAkt-K. (see SI Section 4 ‘Docking studies of TcAkt and human Akt inhibitors capivasertib and PIT-1’).
