Figure 2 | Scientific Reports

Figure 2

From: Construction and verification of a histone deacetylases-related prognostic signature model for colon cancer

Figure 2

Construction of HDAC-related signature. Notes: (A) Forest plots reflected the prognostic genes. (B, C) Cvfit and lambda curves displaying both LASSO regression analysis and coefficient profiles of the 7 genes related to HDAC. (D) Forest plot for the multivariate analysis of hub genes. (E) An analysis of risk scores, survival status, and hub gene expression distribution. (F) Survival curve of TCGA and (G) GEO cohorts. (H) ROC Curve Analysis of the Risk Score for TCGA Dataset. The graph illustrates the predictive performance of the risk score over different timeframes. (I) ROC Curve Analysis of the Risk Score for GEO Dataset. (J) Survival curves of hub genes. (K) Comparing hub gene expressions between tumors and normal tissues. *p < 0.05, **p < 0.01, ***p < 0.001.

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