Table 3 Summary of results obtained after hotnet2 analysis. For each subnetwork, the table shows the minimum K for which subnetworks of size ≥ K are significant (p-value).
From: Dysregulated gene subnetworks in breast invasive carcinoma reveal novel tumor suppressor genes
S.No. | Components | K | p-value |
|---|---|---|---|
1 | MYRIP, AMH, MYO7A, DDR2, PCSK5, PTPRM, CDH23, CDH1 | 8 | 0.01 |
2 | SYT2, SYT9, SYT6, NLGN1, NLGN3, SYT13, NRXN1 | 7 | 0 |
3 | PLIN2, APOB, LIPE, PLIN1, SEC61A2, STAR | 6 | 0.01 |
4 | MAML2, DLL4, NOTCH4, NOTCH2, DTX1, JAG1 | 6 | 0.032 |
5 | VCAN, DNAH6, FBN1, EFEMP2, SELP, MFAP5 | 6 | 0.032 |
6 | UNC5B, SYNE1, NEO1, NTN4, TTC3, TTN, MYOM1, MYOM2 | 8 | 0.01 |
7 | VCAN, DNAH6, FBN1, ADAMTSL5, MFAP4, SELP, MFAP5 | 7 | 0 |
8 | CHL1, CEP120, DMD, NFASC, GALK2, ANK1, ANK2, EHD2, CCDC18, L1CAM, NBPF1, TNS1, AHNAK, NBPF3 | 10 | 0.01 |
9 | DAB1, APLP1, APOB, LRP2, CKLF, PCDHA6, PCDHA3, RELN, SLC12A4, ZDHHC11, CUBN | 10 | 0.01 |
