Table 4 Summary of each component of the subnetwork. The table is showing heat score and fold change of each component. The status and mRNA expression of the components in expression atlas and Oncomine is also shown.

From: Dysregulated gene subnetworks in breast invasive carcinoma reveal novel tumor suppressor genes

Component

Heat score

Log2 fold change

Expression (RNA-seq data analysis)*

Expression Atlas mRNA

Oncomine mRNA expression

Canonical pathways & p-value

SYT2

0.0079

− 1.03

Down

Down

Down

TR/RXR activation pathway

3.43E−03

SYT9

0.0059

2.09

Up

Down

Up

SYT6

0.0079

− 1.44

Down

Down

Down

NLGN1

0.0059

− 1.93

Down

Down

NLGN3

0.0177

− 1.06

Down

Down

Down

SYT13

0.002

5.67

Up

Down

Up

NRXN1

0.0167

− 2.22

Down

Down

Down

  1. * Log2FC>1 or Log2FC<-1, p-value < 0.05.