Table 6 Summary of each component of the subnetwork in early stage TNBC class. The table also depicts status and mRNA expression of each component in expression atlas and Oncomine.
From: Dysregulated gene subnetworks in breast invasive carcinoma reveal novel tumor suppressor genes
Component | Heat score | Log2 Fold change | Expression (RNA-seq data analysis)* | Expression Atlas mRNA | Oncomine mRNA expression | Canonical pathways & p-value | |
|---|---|---|---|---|---|---|---|
UNC5B | 0.0088 | 1.58 | Up | Up | Up | Netrin signalling, RhoA signalling, and axonal guidance signaling pathways | 2.61e−02, 4.85e−02 and 0.0133 |
SYNE1 | 0.0558 | − 1.68 | Down | Down | Down | ||
NEO1 | 0.0088 | − 1.11 | Down | Down | Up | ||
NTN4 | 0.0049 | − 2.87 | Down | Down | Down | ||
TTC3 | 0.0127 | − 1.17 | Down | Down | Up | ||
TTN | 0.2008 | − 2.9 | Down | Up | Down | ||
MYOM1 | 0.0078 | − 4.15 | Down | Down | Down | ||
MYOM2 | 0.0147 | − 1.9 | Down | Down | Down | ||
