Figure 7 | Scientific Reports

Figure 7

From: Efficacy of interstitial photodynamic therapy using talaporfin sodium and a semiconductor laser for a mouse allograft glioma model

Figure 7

Pathological findings of intra tumoral micro-vessels in the 150 mW/cm2 and 100 J/cm2 irradiation groups. (A,C) Immunohistochemical staining using an anti-CD31 antibody, (B) PTAH staining, (D–F) electron microscopic findings. Asterisk: the area of ghost cells, Yellow arrow head: micro-vessels in the layer of apoptotic tumor cells. Tumor micro-vessels in the layer of apoptotic tumor cells was filled with PTAH-positive fibrin thrombi, and had also lost their CD-31 expression. (A–C) Endothelial cells of the micro-vessels in this layer (E,F) demonstrated degeneration compared with the viable tumor cell layer (D).

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