Table 1 The half-maximal inhibitory concentration (IC50) of compounds 7a-7t.

From: Discovery of gefitinib-1,2,3-triazole derivatives against lung cancer via inducing apoptosis and inhibiting the colony formation

Compd No.

IC50 (μM)

H1299

A549

1437

7a

3.94 ± 0.17

3.16 ± 0.11

1.83 ± 0.13

7b

4.60 ± 0.16

5.28 ± 0.20

3.65 ± 0.04

7c

6.24 ± 0.32

5.68 ± 0.14

3.08 ± 0.47

7d

6.04 ± 0.41

8.50 ± 0.41

4.83 ± 0.16

7e

5.81 ± 0.12

4.38 ± 0.07

2.22 ± 0.18

7f

5.65 ± 0.16

16.44 ± 1.07

3.95 ± 0.45

7g

5.97 ± 0.36

6.23 ± 0.12

1.66 ± 0.18

7h

4.89 ± 0.16

7.13 ± 1.21

5.21 ± 0.30

7i

5.60 ± 0.09

5.76 ± 0.62

4.69 ± 0.23

7j

3.84 ± 0.22

3.86 ± 0.38

1.69 ± 0.25

7k

6.90 ± 0.23

4.91 ± 0.52

2.90 ± 0.23

7l

4.92 ± 0.49

6.59 ± 0.20

0.84 ± 0.10

7m

4.48 ± 0.41

6.54 ± 0.21

3.72 ± 0.17

7n

6.02 ± 0.24

3.78 ± 0.03

4.67 ± 0.28

7o

6.78 ± 0.41

12.03 ± 0.15

5.21 ± 0.13

7p

5.04 ± 0.33

8.5 ± 0.34

4.93 ± 0.14

7q

7.68 ± 0.11

9.03 ± 0.15

7.21 ± 0.10

7r

9.35 ± 0.31

12.94 ± 0.25

6.21 ± 0.23

7s

9.68 ± 0.21

11.03 ± 0.25

8.21 ± 0.13

7t

13.04 ± 0.23

13.50 ± 0.33

14.93 ± 0.14

Gefitinib

14.62 ± 0.90

14.62 ± 0.43

20.56 ± 2.45

Back to article page