Figure 2 | Scientific Reports

Figure 2

From: Neurological affection and serum neurofilament light chain in wild type transthyretin amyloidosis

Figure 2

Neurological characterization of patients of different neurological severity. (A,B) Violin plots of NIS subitem scores. (A) Affection of cranial nerves and muscle weakness in patients with NIS < 20 vs NIS ≥ 20. Scores range from 0 to 4 (B) Affection of reflexes, and proximal and distal sensation in patients with NIS < 20 vs NIS ≥ 20. Scores range from 0–2. Data for both left (L) and right (R) body sides are displayed for all items. Detailed legends for both (A) and (B) are depicted in the Score legend A and Score legend B. NIS < 20: n = 33; NIS ≥ 20: n = 13. (C,D) Comparison of nerve conduction studies (NCS) between groups of different neurological affection (by NIS). Statistics: Mann–Whitney-U test. (C) Amplitude peroneal nerve: p = 0.035; conduction velocity peroneal nerve: p = 0.124; distal motor latency peroneal nerve: p = 0.015; NIS < 20: n = 25; NIS ≥ 20: n = 8. (D) Amplitude sural nerve: p = 0.034; conduction sural nerve: p = 0.109; NIS < 20: n = 24; NIS ≥ 20: n = 8.

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