Figure 4 | Scientific Reports

Figure 4

From: Neurological affection and serum neurofilament light chain in wild type transthyretin amyloidosis

Figure 4

Comparison of serum NFL levels in patients with A-ATTRwt with different severity of neuropathy. (A) Boxplots comparing serum neurofilament light chain (sNFL) age and BMI adapted levels (z-scores) as described by Benkert et al.19 of patients with NIS < 20 and NIS ≥ 20. Statistics: unpaired t-test; p = 0.010; NIS < 20: n = 41; NIS ≥ 20: n = 11. (B) Boxplots comparing sNFL z-scores of patients with spinal canal stenosis (SCS) and without SCS. Statistics: unpaired t-test; p = 0.526; SCS: n = 13, no SCS: n = 30.

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