Figure 3
From: Lactobacillus paracasei subsp. paracasei 2004 improves health and lifespan in Caenorhabditis elegans
L. paracasei subsp. paracasei 2004 feeding upregulates the expression of genes related to stress response. (A) Heatmap of differentially expressed genes (DEGs) in response to L. paracasei subsp. paracasei 2004 feeding (FDR cutoff < 0.1, minimum fold change = 2.0). L. paracasei subsp. paracasei 2004 feeding upregulates 1102 genes and downregulates 1817 genes. (B, C) Gene Ontology (GO) analysis of biological processes: the 1102 (> 2.0-fold, FDR < 0.1) upregulated gene list (B) and the 1817 (< 0.5-fold, FDR < 0.1) downregulated gene list were analyzed by PANTHER32. GO terms corresponding to biological processes whose p-value was less than 0.0001 were extracted. (D, E) Bar plots show the expression level of glutathione genes (D) and transcription factors, daf-16 and skn-1 (E).
