Figure 2 | Scientific Reports

Figure 2

From: In vivo bioluminescence imaging of the intracerebral fibroin-controlled AAV-α-synuclein diffusion for monitoring the central nervous system and peripheral expression

Figure 2The alternative text for this image may have been generated using AI.

Representative images of in vivo and ex vivo bioluminescence imaging of the head and brain. (A) Head and (B) brain imaging, of mouse injected with AAV9-SynP-NanoLuc-A53T-a-synuclein without (a) or with (b) fibroin solution. (C,D) Quantitative analysis of bioluminescence signal detected in the head (C) or the brain (D) and expressed in p/sec/cm2/sr. Horizontal lines represent the mean. Each dot represents one head (C) (n = 15, p = 0.0025) or brain (D) (n = 15, p = 0.5) of the injected mouse without fibroin (F−, dark blue) and with fibroin (F+, pink). The bootstrapped mean difference with 95% CI (error bar) is shown on the right side of this graph.

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