Table 2 The enriched GO terms of the five modules covering hub genes.
Module | Category | Term | Gene count | FDR |
|---|---|---|---|---|
0 | CC | Plasma membrane | 81 | 2.92E−14 |
0 | CC | Cytoplasm | 70 | 5.82E−14 |
1 | CC | Mitochondrion | 32 | 1.78E−15 |
2 | CC | Nucleus | 33 | 1.29E−14 |
3 | CC | Nucleoplasm | 32 | 3.55E−15 |
3 | CC | Chromatin | 26 | 3.55E−15 |
4 | CC | Endoplasmic reticulum membrane | 12 | 2.67E−09 |
0 | BP | Signal transduction | 34 | 6.00E−12 |
0 | BP | Platelet activation | 25 | 2.21E−14 |
0 | BP | Negative regulation of apoptotic process | 23 | 7.53E−11 |
0 | BP | Inflammatory response | 22 | 2.61E−11 |
0 | BP | Positive regulation of cell migration | 20 | 1.83E−13 |
1 | BP | Mitochondrial electron transport, NADH to ubiquinone | 46 | 7.11E−15 |
1 | BP | Mitochondrial respiratory chain complex I assembly | 46 | 7.11E−15 |
2 | BP | Cell division | 17 | 2.92E−14 |
2 | BP | Regulation of cyclin-dependent protein serine/threonine kinase activity | 12 | 2.92E−14 |
3 | BP | Negative regulation of transcription by RNA polymerase II | 25 | 2.41E−14 |
3 | BP | Positive regulation of transcription by RNA polymerase II | 28 | 2.41E−14 |
3 | BP | Negative regulation of transcription, DNA-templated | 17 | 5.43E−14 |
3 | BP | Positive regulation of transcription, DNA-templated | 18 | 5.77E−14 |
3 | BP | Regulation of transcription by RNA polymerase II | 17 | 4.92E−07 |
4 | BP | Long-chain fatty acid biosynthetic process | 6 | 2.02E−10 |
4 | BP | Xenobiotic metabolic process | 6 | 3.52E−08 |
0 | MF | ATP binding | 54 | 8.33E−15 |
0 | MF | Protein kinase binding | 26 | 4.12E−14 |
1 | MF | NADH dehydrogenase (ubiquinone) activity | 43 | 2.78E−15 |
1 | MF | Electron transfer activity | 6 | 9.82E−07 |
2 | MF | Protein kinase binding | 15 | 1.80E−12 |
3 | MF | Transcription factor binding | 18 | 4.33E−15 |
3 | MF | Zinc ion binding | 20 | 4.33E−15 |
3 | MF | Nuclear receptor activity | 18 | 4.33E−15 |
4 | MF | Iron ion binding | 8 | 5.03E−11 |
