Table 1 Demographic, clinical, and laboratory characteristics of 181,804 patients on hemodialysis based on the dialyzer classification.
From: Current dialyzer classification in Japan and mortality risk in patients undergoing hemodialysis
Variable | I a | II a | II b | S | P-value |
|---|---|---|---|---|---|
n (%male) | 102,992 (61.4) | 64,155 (70.9) | 4325 (76.1) | 10,332 (57.1) | < 0.0001 |
Age, years | 71.1 ± 11.8 | 66.4 ± 12.1 | 63.3 ± 11.9 | 73.9 ± 11.2 | < 0.0001 |
Vintage, months | 60 [27–120] | 78 [37–144] | 88 [43–165] | 54 [24–107] | < 0.0001 |
Cause of ESKD | < 0.0001 | ||||
Diabetic nephropathy | 39.8 | 39.7 | 36.6 | 39.8 | |
Chronic glomerulonephritis | 28.7 | 31.6 | 35.7 | 27.3 | |
Nephrosclerosis | 12.7 | 10.8 | 10.5 | 13.8 | |
Others | 18.8 | 17.9 | 17.2 | 19.1 | |
Diabetes mellitus, % | 54.6 | 54.3 | 48.2 | 55.7 | < 0.0001 |
Comorbid CVD, % | 35.4 | 31.8 | 29.1 | 37.7 | < 0.0001 |
Systolic BP, mmHg | 150 ± 25 | 152 ± 24 | 152 ± 24 | 150 ± 26 | < 0.0001 |
Diastolic BP, mmHg | 76 ± 14 | 79 ± 15 | 81 ± 15 | 76 ± 15 | < 0.0001 |
Heart rate, bpm | 74 ± 13 | 75 ± 13 | 76 ± 13 | 74 ± 13 | < 0.0001 |
Body mass index, kg/m2 | 21.2 ± 3.8 | 22.4 ± 4.2 | 22.8 ± 4.2 | 20.7 ± 3.7 | < 0.0001 |
Serum urea nitrogen, mg/dL | 59.8 ± 15.9 | 61.4 ± 15.4 | 61.5 ± 14.5 | 56.4 ± 16.2 | < 0.0001 |
Creatinine, mg/dL | 9.3 ± 2.8 | 10.5 ± 2.7 | 11.0 ± 2.6 | 8.4 ± 2.7 | < 0.0001 |
β2-microglobulin, mg/L | 27.0 ± 7.0 | 27.2 ± 6.3 | 27.6 ± 6.4 | 27.9 ± 8.3 | < 0.0001 |
Kt/V | 1.45 ± 0.31 | 1.49 ± 0.30 | 1.52 ± 0.31 | 1.41 ± 0.31 | < 0.0001 |
Serum albumin, g/dL | 3.5 ± 0.5 | 3.6 ± 0.4 | 3.6 ± 0.4 | 3.3 ± 0.5 | < 0.0001 |
Hemoglobin, g/dL | 10.8 ± 1.3 | 11.0 ± 1.3 | 11.1 ± 1.3 | 10.6 ± 1.4 | < 0.0001 |
C-reactive protein, mg/dL | 0.16 [0.06–0.52] | 0.14 [0.05–0.42] | 0.14 [0.06–0.39] | 0.20 [0.07–0.68] | < 0.0001 |
Calcium, mg/dL | 8.7 ± 0.7 | 8.7 ± 0.7 | 8.7 ± 0.7 | 8.5 ± 0.8 | < 0.0001 |
Phosphate, mg/dL | 5.1 ± 1.4 | 5.3 ± 1.5 | 5.5 ± 1.5 | 5.1 ± 1.5 | < 0.0001 |
Intact-PTH, pg/mL | 126 [69–204] | 136 [77–214] | 140 [81–222] | 123 [66–202] | < 0.0001 |
