Table 1 Baseline data, risk factors and outcome in patients with and without PH (postoperative intracranial hemorrhage).

From: Author Correction: Venous thromboembolism and intracranial hemorrhage in patients undergoing glioblastoma surgery

Characteristics1

Total (N = 331)

ICH (N = 13)

No ICH (N = 318)

p value2

Sex (female)

127 (38.4%)

4 (30.8%)

123 (38.7%)

0.773

Age (years)

64.29 ± 12.65

68.69 ± 9.13

64.11 ± 12.75

0.240

BMI (kg/m2)

26.20 ± 4

26.17 ± 4.03

26.20 ± 4.01

0.838

Smoker

50 (15.3%)

0

50 (15.9%)

0.231

Diabetes

45 (13.6%)

2 (15.4%)

43 (13.5%)

0.629

Hypertension

195 (58.9%)

9 (69.2%)

186 (58.5%)

0.570

Atrial fibrillation

23 (6.9%)

1 (7.7%)

22 (6.9%)

1.00

Previous resection

87 (26.3%)

2 (15.4%)

85 (26.7%)

0.526

Therapeutic AC in patient medication

22 (6.6%)

1 (7.7%)

21 (6.6%)

0.598

Anti-platelet-therapy in patient medication

43 (13.2%)

1 (8.3%)

42 (13.4%)

1.00

American Society of Anesthesiologists Score < 3

193 (59.2%)

8 (61.5%)

185 (59.1%)

1.00

Preoperative prophylactic AC with LMWH

244 (76.7%)

10 (76.9%)

234 (76.7%)

1.00

Preoperative prophylactic AC with LMWH (Hours)

22.66 ± 12.49

22.10 ± 11.95

22.68 ± 12.53

0.274

Extent of resection (biopsy)

45 (13.8%)

2 (16.7%)

43 (13.7%)

0.674

Duration of surgery (minutes)

226.94 ± 101.91

280.17 ± 159.45

224.92 ± 98.90

0.368

Lowest body temperature intraoperatively (°C)

36.05 ± .49

35.77 ± .44

36.07 ± .49

0.028*

Blood products intraoperatively

6 (1.8%)

2 (15.4%)

4 (1.3%)

0.020*

Highest sys. blood pressure intraoperatively (mmHg)

133.67 ± 18.23

144.62 ± 30.72

133.21 17.45

.295

Initiation of prophylactic AC after surgery (hours)

34.09 ± 15.02

54.50 ± 25.28

33.43 ± 14.16

 < .001***

Time spend at intensive care unit (hours)

53.95 ± 86.85

206.15 ± 182.19

47.68 ± 74.79

 < .001***

Thromboembolic event

8 (2.4%)

3 (23.1%)

5 (1.6%)

.002**

Therapeutic AC within seven days after surgery

13 (3.9%)

3 (23.1%)

10 (3.1%)

.011*

Cardiopulmonary resuscitation

5 (1.5%)

1 (7.7%)

4 (1.3%)

.183

In-hospital mortality

16 (4.8%)

1 (7.7%)

15 (4.7%)

.481

Death within 30 days

22 (7.2%)

2 (20%)

20 (6.8%)

.157

Death within three months

55 (19.5%)

3 (33.3%)

52 (19.0%)

.384

Modified Rankin Scale at discharge < 4

217 (65.8%)

4 (30.8%)

213 (67.2%)

.013*

Modified Rankin Scale at three months < 4

157 (60.6%)

3 (33.3%)

154 (61.6%)

.161

  1. BMI body mass index, LMWH low molecular weight heparine, AC anticoagulation.
  2. 1Categorical variables are presented with the number and percentage of patients to whom the characteristic applies, Continuous variables are presented with the mean ± the standard deviation.
  3. 2Categorical variables are calculated using Fisher's exact test (2-sided); Continuous variables are calculated using Mann–Whitney U test (2-sided).
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