Figure 2

Representative photographs and analysis of the wound closure rates. (a) Following the induction of dorsal excisional wounds, scabs formed in all rats during the wound healing process. The wound was smaller in the three treatment groups (Groups B–D) on day 14 after the scab was removed. The wound, after being ablated by irreversible electroporation (IRE; Groups C–D), appeared less dark than those that did not undergo IRE (Groups A–B). (b) Representative photograph demonstrating the measurement of wound area; green dotted lines indicate the initial defect and yellow dotted lines indicate the remaining defect. (c) Comparison of changes in the wound area among the groups that demonstrated a significant reduction in the wound area after the combination of EW-7197 and IRE was applied. CI confidence interval.