Figure 6

Comparison of electrochemical biosensor and RT-qPCR method. (A) The detection of extracellular vesicles miR-4732-5p in BPN and early LUAD patients using the RT-qPCR method. ****p < 0.0001 (Mann–Whitney U test). (B) The detection of extracellular vesicles miR-4732-5p in BPN and early LUAD patients using the electrochemical biosensor. ****p < 0.0001 (Mann–Whitney U test). (C) The detection of extracellular vesicles miR-4732-5p in BPN and early LUAD patients using the RT-qPCR method and the electrochemical biosensor. p < 0.0001 (Pearson correlation).