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Figure 1

From: Saponins from Allii Macrostemonis Bulbus attenuate atherosclerosis by inhibiting macrophage foam cell formation and inflammation

Figure 1

SAMB attenuated atherosclerosis in ApoE−/− mice induced by a high-fat diet. (A) Oil-red-O staining of the full-length aorta from the ApoE−/− mice. (B–E) Quantification of the plaques in the full-length aorta, aortic arch, thoracic aorta, and abdominal aorta. (F) Masson, Oil red O, and H&E staining of the aortic root from the ApoE−/− mice (× 200). (G,K) Quantification of collagen fiber content, intra-plaque fat content, plaque area, necrotic lesion area, and fibrous cap thickness in aortic root plaque. The aortic and root sections of 9 mice in each group were utilized for statistical analysis. Data are mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 vs HFD.

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