Figure 2 | Scientific Reports

Figure 2

From: Saponins from Allii Macrostemonis Bulbus attenuate atherosclerosis by inhibiting macrophage foam cell formation and inflammation

Figure 2

SAMB suppressed the infiltration of macrophages in the aortic root and reduced serum levels of inflammatory factors in the ApoE−/− mice with a high-fat diet feeding. (A) CD68 immunofluorescence staining in the aortic root from the ApoE−/− mice (× 200); (B) Quantification of the positive staining of CD68 in aortic root plaque. (C–E) Serum levels of IL-6, TNF-α and IL-1β in the ApoE−/− mice. The aortic root sections of 6 mice in each group were utilized for statistical analysis. Data are mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 vs HFD.

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