Table 4 Multivariate Cox regression analysis for all-cause mortality associated with UACR and UNAPCR mutually adjusted.

From: Urinary non-albumin protein-creatinine ratio is an independent predictor of mortality in patients with type 2 diabetes: a retrospective cohort study

 

HR (95%CI)

p value

UACR ≥ 30 mg/g

1.046 (0.820–1.334)

0.717

UNAPCR ≥ 120 mg/g

1.655 (1.324–2.070)

 < 0.001

Age (year)

1.058 (1.049–1.066)

 < 0.001

Hypertension (yes vs. no)

0.744 (0.458–1.208)

0.231

CVD (yes vs. no)

1.333 (0.940–1.890)

0.106

Cancer (yes vs. no)

1.431 (1.224–1.674)

 < 0.001

Glomerular disease (yes vs. no)

1.439 (1.191–1.739)

 < 0.001

BMI ≥ 24 (kg/m2)

0.801 (0.684–0.938)

0.006

HbA1c (%)

1.088 (1.044–1.133)

 < 0.001

CKD* (yes vs. no)

1.426 (1.182–1.720)

 < 0.001

Triglycerides ≥ 1.7 (mmol/L)

0.956 (0.815–1.123)

0.587

GPT (U/L)

1.002 (0.999–1.005)

0.175

Hb (g/L)

0.891 (0.855–0.929)

 < 0.001

Statin use (yes vs. no)

0.811 (0.694–0.947)

0.008

DPP-4 inhibitor use (yes vs. no)

0.782 (0.671–0.913)

0.002

RAS blockade use (yes vs. no)

1.189 (1.014–1.395)

0.033

Insulin use (yes vs. no)

1.372 (1.160–1.624)

 < 0.001

  1. P value for interaction effect between UACR and UNAPCR on all-cause mortality was 0.126. *CKD was defined as eGFR < 60 mL/min/1.73 m2. Variables with p value < 0.05 in the univariate Cox regression analysis in Table 2 were entered into the multivariate Cox regression analysis.
  2. BMI body mass index, CKD chronic kidney disease, CVD cardiovascular disease, DPP-4 dipeptidyl peptidase-4, eGFR estimated glomerular filtration rate, GPT glutamate pyruvate transaminase, Hb hemoglobin, HbA1c hemoglobin A1c, RAS renin-angiotensin system, UACR urine albumin-to-creatinine ratio, UNAPCR urine non-albumin protein-creatinine ratio.
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