Table 2 Plasma levels of B-type natriuretic peptide (BNP), ELABELA, Apelin, and left ventricular ejection fraction (LVEF) for heart failure (HF) patients by New York Heart Association (NYHA) grade.

From: Decreased plasma ELABELA level as a novel screening indicator for heart failure: a cohort and observational study

Parameters

Non-HF (n = 119)

HF (n = 216)

NYHA I (n = 57)

NYHA II (n = 32)

NYHA III (n = 39)

NYHA IV (n = 88)

Plasma BNP, pg/ml

55.1 ± 19.2

142.3 ± 35.8***

327.7 ± 72.5***###

684.0 ± 164.2***###$$$

3874.7 ± 649.7***###$$$&&&

Plasma ELABELA, ng/ml

13.7 ± 3.0

10.7 ± 2.9*

9.2 ± 2.5***##

7.2 ± 3.4***###$

5.5 ± 3.6***###$$$&&

Plasma Apelin, pg/ml

51.9 ± 19.6

90.7 ± 15.1

209.4 ± 34.5***#

161.8 ± 25.3***##

181.3 ± 38.7***#

LVEF, %

64.3 ± 4.3

63.5 ± 6.2

62.7 ± 7.3

59.9 ± 8.4***#

58.1 ± 9.9***###$

  1. *P < 0.05 and ***P < 0.001 vs. Non-HF; #P < 0.05, ##P < 0.01, and ###P < 0.001 vs. NYHA I; $P < 0.05 and $$$P < 0.001 vs. NYHA II; &&P < 0.01 and &&&P < 0.001 vs. NYHA III.
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