Table 1 Patient and tumor characteristics according to the treatment group at the time of diagnosis.

From: Comparison of anthracycline-containing and anthracycline-free regimens in neoadjuvant HER-2 positive breast cancer treatment

 

Arm A

Arm B

p value

n (%)

n (%)

Age (mean, SD)

53 (± 11)

48 (± 11)

0.01b

Comorbidity

20 (40.0)

32 (34.8)

0.53

ECOG

0.06

 0

34 (68.0)

48 (52.2)

 

 1

16 (32.0)

44 (47.8)

 

Clinical T stage

0.58

 T1–2

38 (76.0)

66 (71.7)

 

 T3–4

12 (24.0)

26 (28.3)

 

Clinical N stage

0.58

 N0

5 (10.0)

11 (12.0)

 

 N1

15 (30.0)

37 (40.2)

 

 N2

23 (46.0)

34 (37.0)

 

 N3

7 (14.0)

10 (10.8)

 

Clinical stage

0.14

 Operable

20 (40.0)

45 (48.9)

 

 Locally advanced

30 (60.0)

43 (46.7)

 

 Inflammatory

0 (0.0)

4 (4.3)

 

Hormone status

0.99

 ER and/or PR-positive

31 (62.0)

57 (62.0)

 

 ER and PR-negative

19 (38.0)

35 (38.0)

 

Grade

0.47

 Gx/G1/G2

26 (52.0)

42 (45.7)

 

 G3

24 (48.0)

50 (54.3)

 

Ki-67 levela (%)

30 (7–90)

40 (8–95)

0.66

Lymphovascular invasion

21 (42.0)

41 (44.6)

0.76

Perineural invasion

15 (30.0)

22 (23.9)

0.43

Number of cyclesa

4 (3–6)

8 (6–8)

< 0.001b

Neoadjuvant treatment completion

46 (92.0)

88 (95.7)

0.45

  1. aPresented with the median instead of n, min–max instead of %.
  2. bStatistically significant.