Figure 9

Principal component analysis (PCA) of isocitrate lyase in three systems, namely Apoenzyme (apoenzyme system, a), Control (isocitrate lyase-ZINC2111081 complex, b) and Dihydroergotamine (isocitrate lyase-dihydroergotamine complex, c), and (d) the overlaid PCA plot of three systems. Only the C-alpha atoms are considered.