Table 2 Nutritional and body composition characteristics of patients with cancer according to tumor type and metastasis (N = 635).

From: Examining variations in body composition among patients with colorectal cancer according to site and disease stage

Characteristics

Total (N = 635)

Colon (n = 310)

Rectum (n = 324)

p

Without metastasis (n = 485)

With metastasis (n = 150)

p

Body mass index

24.7 ± 4.5

24.4 ± 4.3

25.1 ± 4.7

0.057a

25.0 ± 4.6

24.0 ± 4.2

0.016a

 Underweight

41 (6.5%)

20 (6.5%)

21 (6.5%)

0.102c

29 (6.0%)

12 (8.0%)

0.137c

 Normal range

310 (48.8%)

167 (53.9%)

143 (44.1%)

 

229 (47.2%)

81 (54.0%)

 

 Overweight

203 (32.0%)

88 (28.4%)

115 (35.5%)

 

158 (32.6%)

45 (30.0%)

 

 Obesity

81 (12.8%)

36 (11.6%)

45 (13.9%)

 

69 (14.2%)

12 (8.0%)

 

Body composition

 SAT (cm2)

144.3 ± 82.2

142.9 ± 81.9

145.6 ± 82.6

0.680a

146.3 ± 85.2

137.8 ± 71.8

0.269a

 VAT (cm2)

117.5 ± 79.7

115.7 ± 77.9

118.8 ± 81.7

0.630a

121.9 ± 83.0

102.5 ± 66.5

0.004a

 IMAT (cm2)

10.2 ± 7.5

9.7 ± 7.0

10.7 ± 8.0

0.068a

10.5 ± 7.7

9.4 ± 6.8

0.137a

 SM (cm2)

124.1 ± 32.9

120.4 ± 33.0

125.5 ± 32.9

< 0.001a

124.4 ± 33.7

118.6 ± 30.3

0.048a

 SMI (cm2/m2)

46.5 (39.5, 53.9)

45.2 (37.9, 52.0)

48.3 (41.0, 54.9)

< 0.001b

46.9 (39.6, 54.2)

45.5 (39.1, 52.5)

0.223b

 SMD (HU)

33.5 (27.1, 39.2)

33.9 (27.2, 39.2)

32.9 (27.1, 39.1)

0.546b

33.2 (26.9, 39.2)

33.8 (27.8, 38.9)

0.855b

Body composition abnormalities

 Low SMI

237 (37.3%)

135 (43.5%)

102 (31.5%)

0.002c

178 (36.7%)

59 (39.3%)

0.560c

 Low SMD

436 (68.7%)

213 (68.7%)

223 (68.8%)

0.927c

327 (67.4%)

109 (72.7%)

0.226c

 High VAT

286 (45.0%)

139 (44.8%)

147 (45.4%)

0.864c

229 (47.2%)

57 (38.0%)

0.047c

  1. SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue; IMAT, intermuscular adipose tissue; SM, skeletal muscle mass; SMI, skeletal muscle index; SMD, skeletal muscle radiodensity; UH, Hounsfield Units; BMI, body mass index. Data presented as median and interquartile range (P25, P75).
  2. Low SMI: < 41 cm2/m2, regardless of BMI for women; < 43 cm2/m2 when BMI < 25 kg/m2 or < 53 cm2/m2 when BMI > 25 kg/m2; for men.
  3. Low SMD: < 41 UH when BMI < 24.9 kg/m2 and < 33 UH when BMI > 25 kg/m2 for both sexes.
  4. High VAT: 163.8cm2 for men and 80.1cm2 for women.
  5. aIndependent t student, bMann-Witney and cChi-squared tests performed.
  6. Significant values are in [bold].