Table 3 Comparison of S-antibody titers between two consecutive visits in group II participants*.

From: Antibody longevity and waning following COVID-19 vaccination in a 1-year longitudinal cohort in Bangladesh

 

Pfizer

Moderna

AstraZeneca

Sinopharm

Between visit 1 & 2

    

RT-PCR positive

n = 5

n = 4

n = 9

n = 31

Visit 1

8872 ± 12.2

4193 ± 14.3

1706 ± 8.87

875.2 ± 10.2

Visit 2

11,609 ± 31.5

11,262 ± 13.0

27,996 ± 38.5

4390 ± 12.7

P value

 < 0.001

0.031

 < 0.001

 < 0.001

COVID-like symptoms

n = 0

n = 2

n = 1

n = 8

Visit 1

–

9676 ± 11.3

6050

1665 ± 15.3

Visit 2

–

49,522 ± 30.5

8407 ± 23.4

7791 ± 10.5

P value

 

–

–

 < 0.001

Between visit 2 & 3

    

RT-PCR positive

n = 23

n = 20

n = 8

n = 26

Visit 2

5942 ± 19.2

8270 ± 16.1

327.3 ± 12.2

851.5 ± 11.2

Visit 3

11,695 ± 12.3

23,823 ± 11.0

3548 ± 15.1

7200 ± 12.8

P value

 < 0.001

 < 0.001

 < 0.001

 < 0.001

COVID-like symptoms

n = 5

n = 3

n = 5

n = 6

Visit 2

5587 ± 11.3

2930 ± 14.1

657.0 ± 9.57

1529 ± 16.3

Visit 3

9068 ± 11.3

10,629 ± 13.1

2828 ± 13.3

3971 ± 12.4

P value

 < 0.001

0.034

 < 0.001

 < 0.001

Between visit 3 & 4

    

RT-PCR positive

n = 7

n = 6

n = 5

n = 4

Visit 3

4749 ± 21.4

3990 ± 23.5

708.6 ± 14.6

2826 ± 12.7

Visit 4

12,445 ± 19.0

18,355 ± 29.0

14,171 ± 19.3

13,412 ± 16.8

P value

 < 0.001

 < 0.001

 < 0.001

 < 0.001

COVID-like symptoms

n = 3

n = 5

n = 2

n = 0

Visit 3

5161 ± 23.0

6734 ± 19.4

1945 ± 27.8

–

Visit 4

10,972 ± 21.9

14,662 ± 18.2

19,511 ± 13.0

–

P value

0.045

 < 0.001

–

 
  1. Data are presented as GM ± SD. Multivariate regression model was used to calculate the estimated mean and the regression model was adjusted by age, sex, household income, occupation and BMI. *Group II consists of individuals, who got infected with SARS-CoV-2 (tested positive by RT-PCR or showed COVID-like symptoms and positive for N-antibodies) and did not receive a 3rd dose of vaccine during the study period. BMI: Body mass index; SARS-CoV-2: Severe acute respiratory coronavirus-2; RT-PCR: Reverse transcription polymerase chain reaction; GM: Geometric mean; SD: Standard deviation.
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