Table 2 K-means clustering of gene expression patterns displayed by gene ontology biological process.
Cluster | adj.Pval | nGenes | Pathways | Genes |
|---|---|---|---|---|
A | 5.36E−52 | 74 | Extracellular matrix organization | COL11A1 COL16A1 ADAMTS2 MMP2 MMP11 COL1A1 MMP19 COL10A1 COL5A1 POSTN LOXL2 COL4A2 SULF1 COL8A1 SERPINH1 PDPN COL1A2 COL3A1 COL4A1 COL4A5 COL5A2 COL15A1 FAP AEBP1 TPSAB1 ELN FBLN1 CCDC80 CRISPLD2 COMP ENG NID1 CCN2 FMOD PDGFRA CYP1B1 EMILIN1 LUM FKBP10 CCN1 SFRP2 DDR2 OLFML2B ANTXR1 EFEMP2 LCP1 GREM1 SH3PXD2B COL12A1 ITGAL DCN VCAN NID2 TIMP1 SERPINE1 SH3PXD2A SPARC FN1 MFAP2 LRP1 MATN3 CTSL ITGA11 COL6A1 COL6A2 CTSK ADAM12 ITGB2 COL6A3 HTRA1 FBN1 A2M BGN PECAM1 |
A | 6.07E−29 | 92 | Cell adhesion | MYL9 NID2 PTK7 FN1 CCN2 PLAU PALLD COL5A1 POSTN PLXNC1 GPNMB PARVG CDH11 CCN1 THY1 VSIG4 SPON2 ITGB2 PDPN OLR1 ITGBL1 PECAM1 SPON1 SNAI2 FBLN1 COL16A1 SERPINE1 SPOCK1 IGFBP7 FBN1 CERCAM COL3A1 ANTXR1 LEP RAP2B LILRB4 HLA-DRB1 HLA-DRA AIF1 ITGAL STAB1 CD4 CD74 VCAN SPI1 FAP PTPRC CCDC80 LGALS1 CORO1A COMP ENG COL1A1 NRXN2 COL12A1 NID1 CSF3R LRP1 EMILIN2 LRRC32 ITGA11 CYP1B1 EMILIN1 COL6A1 COL6A2 COL8A1 BOC ADAM12 SPARCL1 MXRA8 COL6A3 GREM1 AXL IL7R HLA-DQB1 NTM THBS2 COL15A1 DUSP1 PDGFRA HLA-DPA1 EFEMP2 HLA-DPB1 HLA-DMB SFRP1 SFRP2 LAPTM5 CCL19 ARHGDIB ISLR LOXL2 DDR2 |
A | 6.57E−29 | 32 | Collagen fibril organization | COL5A1 LOXL2 SERPINH1 AEBP1 COL11A1 ADAMTS2 MMP11 COMP FMOD CYP1B1 EMILIN1 LUM FKBP10 SFRP2 DDR2 COL5A2 COL1A1 COL1A2 GREM1 COL3A1 EFEMP2 COL12A1 COL16A1 COL10A1 COL4A2 COL6A1 COL6A2 COL8A1 COL6A3 COL4A1 COL4A5 COL15A1 |
A | 2.66E−24 | 60 | Blood vessel development | ADGRA2 ISM1 ENG COL1A1 CALD1 ANGPTL2 THY1 THBS2 COL15A1 HSPB6 DCN SPARC NR4A1 SERPINF1 COL4A2 SULF1 LEP SPI1 FAP MMP2 COMP PTK7 FN1 PRRX1 CCN2 TBX2 MMP19 APOE COL5A1 PDGFRA TBX3 CYP1B1 EMILIN1 FKBP10 CCN1 COL8A1 SFRP2 EDNRA FGF18 ITGB2 FMNL3 CYBB GREM1 ANTXR1 SOCS3 COL4A1 C5AR1 SERPINE1 ACTA2 PECAM1 STAB1 PTGIS LOXL2 ADAM12 COL1A2 SFRP1 PDGFRB LRP1 EFEMP2 GPNMB |
A | 3.75E−24 | 61 | Vasculature development | ADGRA2 ISM1 ENG COL1A1 CALD1 ANGPTL2 THY1 THBS2 COL15A1 HSPB6 DCN SPARC NR4A1 SERPINF1 COL4A2 SULF1 LEP SPI1 FAP MMP2 COMP PTK7 FN1 PRRX1 CCN2 TBX2 MMP19 APOE COL5A1 PDGFRA TBX3 CYP1B1 EMILIN1 FKBP10 CCN1 COL8A1 SFRP2 EDNRA FGF18 ITGB2 FMNL3 CYBB GREM1 ANTXR1 SOCS3 COL4A1 C5AR1 SERPINE1 ACTA2 PECAM1 STAB1 PTGIS LOXL2 ADAM12 COL1A2 SFRP1 PDGFRB LRP1 PDPN EFEMP2 GPNMB |
A | 2.72E−22 | 84 | Cell migration | CORO1A ENG PDGFRB PLXNC1 THY1 FGF18 FCER1G ITGB2 FMNL3 PDPN AXL GP2 SDC2 CCL19 CD248 RAP2B ITGBL1 CCL18 ITGAL DCN VCAN FBLN1 FAP SFRP1 SERPINE1 COL1A1 ARHGDIB SPARC FN1 IGFBP5 PLAU NR4A1 APOE PDGFRA GPNMB CCN1 AIF1 PECAM1 CD74 ADGRA2 SPI1 TREM2 IL1R1 CCN2 CSF3R EPX LRP1 PALLD SERPINF1 POSTN CYP1B1 EMILIN1 TRPM2 SFRP2 CXCL14 CYGB DDR2 FSTL1 CTHRC1 GREM1 LDB2 LEP F2R SLC8A1 C5AR1 SNAI2 PTPRC TIMP1 RARRES2 PTK7 DUSP1 COL5A1 LOXL2 LCP1 SULF1 ITGA11 NKD1 SPOCK1 COL3A1 ZEB2 TREM1 JCHAIN COL1A2 OLR1 |
A | 1.02E−21 | 71 | Circulatory system development | ADGRA2 ISM1 ENG COL1A1 FN1 CALD1 TBX3 ANGPTL2 THY1 PDLIM3 THBS2 COL15A1 ELN HSPB6 DCN SPARC NR4A1 SERPINF1 COL4A2 SULF1 LEP COL11A1 SPI1 FAP MMP2 COMP PTK7 PRRX1 ID3 CCN2 TBX2 MMP19 APOE COL5A1 PDGFRA CYP1B1 EMILIN1 FKBP10 CCN1 COL8A1 SFRP2 EDNRA FGF18 ITGB2 FMNL3 CYBB GREM1 ANTXR1 SH3PXD2B SOCS3 COL4A1 C5AR1 SERPINE1 ACTA2 ADAP2 PECAM1 STAB1 PTGIS LOXL2 ADAM12 COL1A2 FBN1 COL3A1 SNAI2 SFRP1 PDGFRB LRP1 PDPN EFEMP2 SLC8A1 GPNMB |
A | 5.07E−21 | 87 | Cell motility | CORO1A ENG PDGFRB PLXNC1 THY1 FGF18 FCER1G ITGB2 FMNL3 PDPN AXL GP2 SDC2 CCL19 CD248 RAP2B CFAP43 ITGBL1 CCL18 ITGAL DCN VCAN FBLN1 FAP SFRP1 SERPINE1 COL1A1 ARHGDIB SPARC FN1 IGFBP5 PLAU NR4A1 APOE PDGFRA GPNMB CCN1 AIF1 PECAM1 CD74 ADGRA2 SPI1 TREM2 IL1R1 CCN2 CSF3R EPX LRP1 PALLD SERPINF1 POSTN CYP1B1 EMILIN1 TRPM2 SFRP2 CXCL14 CYGB DDR2 FSTL1 CTHRC1 GREM1 LDB2 LEP CAVIN1 F2R SLC8A1 C5AR1 SNAI2 PTPRC TIMP1 RARRES2 PTK7 DUSP1 COL5A1 LOXL2 LCP1 SULF1 ITGA11 NKD1 SPOCK1 SLC9B1 COL3A1 ZEB2 TREM1 JCHAIN COL1A2 OLR1 |
A | 9.64E−20 | 51 | Blood vessel morphogenesis | ADGRA2 ISM1 ENG CALD1 ANGPTL2 THY1 THBS2 COL15A1 HSPB6 DCN SPARC NR4A1 SERPINF1 COL4A2 SULF1 LEP SPI1 FAP MMP2 COMP FN1 PRRX1 CCN2 TBX2 MMP19 APOE PDGFRA CYP1B1 EMILIN1 FKBP10 CCN1 COL8A1 SFRP2 EDNRA FGF18 ITGB2 FMNL3 CYBB GREM1 COL4A1 C5AR1 SERPINE1 STAB1 PTGIS LOXL2 ADAM12 SFRP1 PDGFRB LRP1 EFEMP2 GPNMB |
A | 1.63E−19 | 90 | Locomotion | CORO1A RARRES2 ENG PDGFRB PALLD PLXNC1 THY1 FGF18 FCER1G ITGB2 FMNL3 PDPN AXL GP2 SDC2 CCL19 CD248 RAP2B CFAP43 ITGBL1 CCL18 ITGAL DCN VCAN FBLN1 FAP SFRP1 SERPINE1 COL1A1 ARHGDIB SPARC FN1 IGFBP5 PLAU NR4A1 APOE PDGFRA GPNMB CCN1 AIF1 PECAM1 CD74 ADGRA2 SPI1 TREM2 PTK7 IL1R1 CCN2 CSF3R EPX LRP1 LSP1 SERPINF1 POSTN CYP1B1 EMILIN1 TRPM2 BOC SFRP2 CXCL14 CYGB DDR2 FSTL1 CTHRC1 GREM1 LDB2 LEP CAVIN1 F2R SLC8A1 FPR3 C5AR1 SNAI2 PTPRC TIMP1 DUSP1 COL5A1 LOXL2 LCP1 SULF1 ITGA11 NKD1 SPOCK1 SLC9B1 COL3A1 ZEB2 TREM1 JCHAIN COL1A2 OLR1 |
A | 1.11E−18 | 110 | Anatomical structure morphogenesis | GAS7 TYROBP ADGRA2 LZTS1 ISM1 ENG COL12A1 MFAP2 DUSP1 CALD1 PALLD PDGFRA TBX3 PLXNC1 ANGPTL2 PARVG CDH11 THY1 FGF18 FMNL3 PDPN FBN1 GREM1 SDC2 NPTX1 FAM20C THBS2 COL15A1 ELN HSPB6 DCN FBLN1 SERPINE1 SPARC FN1 INHBA NR4A1 COL5A1 SERPINF1 COL4A2 SULF1 CCN1 ANTXR1 LEP COL5A2 COL11A1 SPI1 FAP SLC1A3 MMP2 TREM2 ACP5 CORO1A SFRP1 COMP ASPN LIPA COL1A1 PTK7 PDGFRB IGFBP5 PRRX1 ID3 CCN2 CSF3R TGFB3 TBX2 MMP19 LRP1 APOE POSTN CYP1B1 EMILIN1 NKD1 FKBP10 CD53 COL8A1 BOC SFRP2 SERPINH1 EDNRA ITGB2 CTHRC1 CYBB HTRA1 AXL IL7R CD248 TMEM119 SOCS3 COL4A1 C5AR1 MAFB LST1 COL6A1 STAB1 CRISPLD2 SH3PXD2A PTGIS LOXL2 ADAM12 COL1A2 SNAI2 ACTA2 ACTG2 EFEMP2 GPNMB DKK3 MGP F2R |
B | 0.000131348 | 66 | System process | GABRA3 GLRA2 CRYBA1 CHRNE NMU TNNI3 SCN7A SCN11A OR5B2 OR5AP2 OR13G1 GAL C1QTNF3 SLIT2 HAND2 LPO KCNMB2 LAMC3 CALCRL TRPM3 SOX10 ZMYND8 AVP TRPA1 CLIC5 SLC8A2 NPY DBH CD36 HTR2B CCN3 SNCA NCAM2 S100B SELENON TMEM100 BEST1 BFSP2 OR4D5 KCND3 OR52W1 GPR4 SLC17A8 NRXN1 SLC9A4 OR4F6 RTL4 OR51I2 FZD9 RELN OR51A2 OPN1MW3 OR52R1 OR8S1 RANGRF KLF2 TFAP2A CACNA2D1 MAPT ANK3 AKAP6 SLC16A1 SORBS1 MEOX2 OTOR HOXB2 |
B | 0.000212035 | 47 | Nervous system process | GABRA3 GLRA2 CRYBA1 CHRNE SCN7A SCN11A OR5B2 OR5AP2 OR13G1 LPO KCNMB2 LAMC3 TRPM3 SOX10 ZMYND8 AVP TRPA1 NMU CLIC5 SLC8A2 DBH TNNI3 CD36 CCN3 SNCA NCAM2 S100B TMEM100 BEST1 BFSP2 OR4D5 OR52W1 SLC17A8 NRXN1 OR4F6 RTL4 OR51I2 FZD9 RELN OR51A2 OPN1MW3 OR52R1 OR8S1 TFAP2A MAPT ANK3 OTOR |
B | 0.005891948 | 57 | Movement of cell or subcellular component | SEMA3B LAMC3 FGF20 SOX10 CCL1 TSPAN11 KIF17 EPHA7 KIF20B MYO1F SLIT2 CFAP157 SDC3 CXCR1 GAP43 CCR9 CLEC14A FAM110C RELN LAMA2 THBS4 CCN3 IGFBP3 DLC1 RET HOXB9 NDNF CSF1 APOD L1CAM RASGEF1A NGFR MMP9 LAMA4 DBH PLP1 HTR2B GDF7 GFRA3 TRIM46 HAND2 SHH KCND3 ROBO2 MEOX2 NAV3 SH3BP1 ZMYND8 RANGRF CACNA2D1 MAPT GTSE1 F10 TNNI3 SHC3 SLC16A1 NRXN1 |
B | 0.005891948 | 11 | Regulation of nervous system process | SOX10 ZMYND8 AVP NMU SLC8A2 CCN3 S100B TMEM100 SCN11A NRXN1 RELN |
B | 0.005891948 | 20 | Regulation of membrane potential | GABRA3 GLRA2 CHRNE SCN7A SCN11A AKAP6 TCL1A RANGRF KCND3 KCNMB2 ZMYND8 SLC8A2 CD36 SNCA NRXN1 RELN CACNA2D1 MAPT ANK3 FZD9 |
B | 0.005891948 | 22 | Axon development | SEMA3B PLP1 EPHA7 SLIT2 GAP43 LAMA2 ROBO2 MAPT L1CAM NGFR GDF7 GFRA3 NCAM2 TRIM46 SHH RET RELN ANK3 APOD SHC3 S100B NRXN1 |
B | 0.00628404 | 51 | Locomotion | SEMA3B LAMC3 FGF20 SOX10 CCL1 TSPAN11 EPHA7 SLIT2 CFAP157 SDC3 CXCR1 GAP43 CCR9 CLEC14A FAM110C RELN LAMA2 THBS4 CCN3 IGFBP3 DLC1 RET HOXB9 NDNF CSF1 ROBO2 APOD L1CAM RASGEF1A NGFR MMP9 LAMA4 DBH PLP1 HTR2B KIF20B GDF7 SNCA GFRA3 TRIM46 HAND2 SHH MEOX2 NAV3 SH3BP1 ZMYND8 GTSE1 F10 SHC3 SLC16A1 NRXN1 |
B | 0.006555771 | 10 | Action potential | SCN7A SCN11A AKAP6 KCNMB2 SLC8A2 CD36 KCND3 RANGRF CACNA2D1 ANK3 |
B | 0.006555771 | 15 | Axon guidance | SEMA3B EPHA7 SLIT2 GAP43 LAMA2 L1CAM NGFR GDF7 GFRA3 SHH ROBO2 RELN SHC3 RET NRXN1 |
B | 0.006924573 | 39 | G protein-coupled receptor signaling pathway | GABRA3 CALCRL GAL GLRA2 CCL1 NMU ADGRG6 GCG HCRTR1 NPY HTR2B GPR119 OR5B2 OR5AP2 GPR4 OPN1MW3 FCN1 SNCA MARCO CXCR1 NPY5R OR4D5 CCR9 OR52W1 BHLHA15 GPR132 OR4F6 OR51I2 FZD9 OR13G1 OR51A2 DGKK OR52R1 OR8S1 GPHA2 AVP PDE1A ARHGEF6 GAP43 |
B | 0.007856876 | 13 | Glial cell differentiation | ADGRG6 PLP1 DAAM2 SHH LAMC3 SOX10 LGI4 S100B TAL1 GAP43 RELN LAMA2 MAPT |
B | 0.009205009 | 42 | Cell migration | SEMA3B LAMC3 FGF20 SOX10 CCL1 TSPAN11 SDC3 CXCR1 CCR9 CLEC14A FAM110C RELN THBS4 CCN3 SLIT2 IGFBP3 DLC1 RET HOXB9 NDNF CSF1 APOD L1CAM RASGEF1A MMP9 LAMA4 DBH PLP1 HTR2B KIF20B GFRA3 TRIM46 HAND2 SHH LAMA2 MEOX2 NAV3 SH3BP1 ZMYND8 GTSE1 F10 SLC16A1 |
B | 0.009462674 | 5 | Response to pain | TRPA1 THBS4 DBH RET RELN |
B | 0.009658947 | 6 | Autonomic nervous system development | SOX10 GFRA3 HAND2 RET HOXB2 TFAP2A |
C | 1.36E−09 | 16 | Humoral immune response | CXCL2 CXCL6 C3 CRP S100A9 CXCL3 CXCL1 CXCL8 C4B SERPING1 DEFB1 FGA CLU CFB CD81 CCL2 |
C | 7.00E−06 | 30 | Defense response | CXCL2 CCL2 CXCL6 CRP S100A9 CXCL3 CXCL1 DEFB1 CXCL8 UBD THBS1 SERPING1 FGA ICAM1 CD81 SPP1 CLU C3 CHI3L1 GJA1 SERPINA1 CFB C4B MMP12 IL32 SCTR NCF2 DCDC2 NCAM1 FLNA |
C | 1.23E−05 | 29 | Response to oxygen-containing compound | CXCL2 GRB10 CXCL6 LYPD1 S100A9 CXCL3 CXCL1 CXCL8 CFTR ICAM1 CCL2 AKAP7 SPP1 THBS1 ATP1A1 TNC HOMER2 SLC39A14 CRYAB SOD2 TNFSF10 GJA1 CLDN3 AGRN HNF1B TPM1 CLU FLNA MMP12 |
C | 1.32E−05 | 42 | Response to organic substance | FSTL3 CXCL2 GRB10 CCL2 PMEPA1 CXCL6 LYPD1 S100A9 CXCL3 CXCL1 CXCL8 UBD LEFTY1 CFTR ICAM1 AKAP7 SPP1 CLU THBS1 ATP1A1 C4B TNC RAP1GAP HOMER2 SLC39A14 CRYAB CD81 SOD2 TNFSF10 SNRPN CHI3L1 GJA1 CLDN3 FLRT2 AGRN MMP12 HNF1B MT1G SLC34A2 FLNA IL32 NCAM1 |
C | 1.32E−05 | 9 | Antimicrobial humoral response | CXCL2 CXCL6 S100A9 CXCL3 CXCL1 CXCL8 DEFB1 FGA CLU |
C | 1.92E−05 | 6 | Humoral immune response mediated by circulating immunoglobulin | CRP CLU C3 SERPING1 C4B CD81 |
C | 1.92E−05 | 7 | Complement activation | C3 CRP C4B SERPING1 CLU CFB CD81 |
C | 1.92E−05 | 25 | Cell adhesion | FGA FLNA ICAM1 CDH6 SPP1 CLDN10 S100A9 CLDN3 CLDN2 FSTL3 CD81 THBS1 CXCL8 PPP1CB MMP12 TNC CNN3 SDC4 AFDN NCAM1 FLRT2 CCL2 TPM1 PKHD1 IL32 |
C | 1.92E−05 | 38 | Response to external stimulus | CXCL2 CCL2 CXCL6 MTUS1 CRP S100A9 CXCL3 CXCL1 DEFB1 CXCL8 FGA UBD SPP1 THBS1 SERPING1 C4B TNC ICAM1 CD81 SOD2 CLU C3 NFIB GJA1 ATP1A1 FLRT2 FLNA CFB MMP12 CHI3L1 TUBB2B CLDN3 SCTR NCAM1 PPP1CB RAP1GAP GRB10 NCF2 |
C | 1.92E−05 | 14 | Regulation of peptidase activity | SERPINA4 HIP1R SERPING1 SERPINA5 SERPINA1 TNFSF10 THBS1 S100A9 TFPI2 CRYAB ITIH5 C3 C4B CLDN3 |
C | 1.92E−05 | 7 | Antimicrobial humoral immune response mediated by antimicrobial peptide | CXCL2 CXCL6 S100A9 CXCL3 CXCL1 CXCL8 DEFB1 |
C | 1.92E−05 | 46 | Regulation of biological quality | FGA FLNA SLC4A4 SLC39A14 KDELR1 SPP1 MT1G SLC34A2 ATP1A1 WNK2 MT1E MT1F AKAP7 CCL2 CLU C3 HIP1R CRP THBS1 CFTR WWTR1 ICAM1 HOMER2 TFPI2 GRB10 SOD2 RBP1 CXCL6 SERPING1 GJA1 GATM FLRT2 AGRN SERPINA1 GTF2I HNF1B CRYAB CD81 TPM1 CLDN3 PKHD1 SCTR ACSM3 NCF2 S100A9 SERPINA5 |
C | 2.75E−05 | 31 | Movement of cell or subcellular component | CXCL2 CCL2 SDC4 CXCL6 MYO1B MTUS1 KIF12 TUBB2B DCDC2 S100A9 CXCL3 CXCL1 CXCL8 FLNA THBS1 MMP12 ICAM1 GRB10 CD81 NFIB ATP1A1 FLRT2 SOD2 AFDN TPM1 GJA1 DEFB1 CLDN3 NCAM1 PKHD1 RAP1GAP |
C | 2.75E−05 | 16 | Response to bacterium | CXCL2 CXCL6 S100A9 CXCL3 CXCL1 DEFB1 CXCL8 CCL2 FGA C4B ICAM1 SOD2 C3 NFIB GJA1 CRP |
D | 3.99E−10 | 4 | Cell wall disruption in other organism | REG1A REG3G REG3A REG1B |
D | 1.09E−08 | 7 | Digestion | CEL PRSS3 CLPS CTRB1 CTRB2 PRSS2 SERPINA3 |
D | 1.09E−08 | 7 | Antimicrobial humoral response | REG1A REG3G REG3A REG1B PLA2G1B PRSS3 PRSS2 |
D | 4.07E−07 | 13 | Proteolysis | PRSS3 CPA1 CELA3A CPB1 CPA2 CTRC CTRB1 CTRB2 SERPINA3 CELA3B PRSS2 SPINK1 INS |
D | 4.66E−07 | 4 | Cobalamin metabolic process | PRSS3 CTRC CTRB1 CTRB2 |
D | 6.99E−07 | 5 | Antimicrobial humoral immune response mediated by antimicrobial peptide | REG1A REG3G REG3A REG1B PLA2G1B |
D | 8.63E−06 | 4 | Acute-phase response | INS REG3G REG3A SERPINA3 |
D | 0.000216407 | 6 | Response to peptide hormone | REG1A REG3G REG3A REG1B INS PLA2G1B |
D | 0.000243582 | 9 | Response to external biotic stimulus | REG1A REG3G REG3A REG1B PLA2G1B INS CLPS PRSS3 PRSS2 |
E | 2.11E−06 | 6 | Maintenance of gastrointestinal epithelium | VSIG1 TFF3 TFF2 TFF1 MUC4 MUC13 |
E | 4.43E−06 | 28 | Response to external biotic stimulus | GSDMB OAS1 PI3 TRIM31 S100A14 APOL1 CD55 UPK1B REG4 TRIM29 PLAC8 HPGD GJB2 IFI27 C15ORF48 FOS PLAAT3 KRT16 FER1L6 CEACAM1 PPARG MUC5B XAF1 MUC4 MUC17 MUC3A MUC13 MUC5AC |
E | 8.23E−06 | 7 | O-glycan processing | MUC5B GCNT3 MUC4 MUC17 MUC3A MUC13 MUC5AC |
E | 1.81E−05 | 9 | Digestion | VSIG1 TFF3 TFF2 TFF1 CAPN9 GCNT3 CAPN8 MUC4 MUC13 |
E | 3.22E−05 | 39 | Response to external stimulus | LAMA3 GSDMB OAS1 PI3 PPARG TRIM31 XCR1 S100A14 F3 APOL1 CD55 WNT11 UPK1B SLC2A1 REG4 TRIM29 PLAC8 HPGD TNFRSF11B GJB2 IFI27 AVPR1A C15ORF48 FOS KRT20 PLAAT3 NQO1 KRT16 FER1L6 MMP28 CEACAM1 PLAT MUC5B XAF1 MUC4 MUC17 MUC3A MUC13 MUC5AC |
E | 0.000206501 | 31 | Biological process involved in interspecies interaction between organisms | GSDMB OAS1 PI3 TRIM31 S100A14 APOL1 TMPRSS4 CD55 UPK1B REG4 TRIM29 PLAC8 CREB3L1 HPGD GJB2 IFI27 C15ORF48 FOS PLAAT3 KRT16 HSPA1A FER1L6 CEACAM1 PPARG MUC5B XAF1 MUC4 MUC17 MUC3A MUC13 MUC5AC |
E | 0.000250704 | 7 | Digestive system process | VSIG1 TFF3 TFF2 TFF1 GCNT3 MUC4 MUC13 |
E | 0.000257976 | 14 | Multicellular organismal homeostasis | VSIG1 TFF3 TFF2 TFF1 PLAC8 TNFRSF11B SFN KRT16 USH1C OAS1 MUC4 MUC13 SLC2A1 ID1 |
E | 0.000270783 | 17 | Epithelial cell differentiation | USH1C UPK1B SPRR1B VSIG1 AGR2 SDC1 ID1 SPRR3 SFN KRT16 WNT11 CEACAM1 PODXL PPARG DHRS9 PI3 KRT20 |
E | 0.000302632 | 10 | Tissue homeostasis | VSIG1 TFF3 TFF2 TFF1 TNFRSF11B USH1C OAS1 MUC4 MUC13 SLC2A1 |
E | 0.000455402 | 20 | Defense response to other organism | GSDMB OAS1 PI3 TRIM31 APOL1 TRIM29 PLAC8 IFI27 KRT16 CD55 S100A14 CEACAM1 PPARG MUC5B XAF1 MUC4 MUC17 MUC3A MUC13 MUC5AC |
F | 2.42E−18 | 52 | Cell adhesion | CDH1 DSG2 NTN4 DSP ITGB8 PERP ITGB6 LAMA5 ITGB4 PTPRF NECTIN4 TNFRSF21 CCL28 PCDH1 CLDN1 PLXNB1 ADAM9 CLDN7 PKP3 CLDN4 PLXNB2 LAMB3 ERBB3 CD46 EPCAM EPHA2 CXADR F11R SPINT2 EFNA1 JUP MUC1 ADGRG1 CD24 ITGA3 BAIAP2L1 LAMC2 KRT18 SOX9 ATP1B1 NFKBIZ MPZL2 PTPRK ITGA2 EZR TESC LIF ASS1 DDR1 FUT3 TACSTD2 CD151 |
F | 2.42E−18 | 62 | Tissue development | LAMC2 NTN4 SOX9 LAMA5 ST14 F11R SEMA4B LAMB3 DSP LIF DAB2IP CD151 AKR1C1 EZR HNF4A KLF5 KRT18 TFCP2L1 ITGB6 DHCR24 IRF6 PPL EPCAM KRT17 RAB25 EHF FLNB SHROOM3 DUOX2 EPHA2 CLDN1 ELF3 ITGA2 SPINT1 SPINT2 EFNA1 FAM83H PLXNB2 ITGA3 MMP15 VIL1 ITGB4 ADAM9 AKR1C3 ANXA4 PROM1 DSG2 MYH14 ITGB8 DDR1 CD24 ESRP1 CXADR TACSTD2 KRT6A KRT23 PERP KRT7 KRT8 KRT19 JUP PKP3 |
F | 1.07E−17 | 39 | Epithelial cell differentiation | ST14 F11R DSP LIF AKR1C1 EZR HNF4A KLF5 KRT18 TFCP2L1 IRF6 PPL SOX9 KRT17 RAB25 EHF FLNB SHROOM3 EPHA2 CLDN1 ELF3 ITGA2 SPINT2 VIL1 ADAM9 AKR1C3 ANXA4 PROM1 CD24 ESRP1 DSG2 KRT23 PERP KRT7 KRT8 KRT19 JUP PKP3 KRT6A |
F | 1.10E−16 | 29 | Skin development | DSP ST14 LSR ITGB6 DHCR24 IRF6 PPL SOX9 KRT17 LAMA5 FLNB CLDN1 ITGA2 JUP ADAM9 AKR1C3 ITGA3 ITGB4 EPHA2 CLDN4 DSG2 KRT23 KRT18 PERP KRT7 KRT8 KRT19 PKP3 KRT6A |
F | 2.99E−16 | 47 | Epithelium development | SOX9 LAMA5 ST14 F11R DSP LIF CD151 AKR1C1 NTN4 EZR HNF4A KLF5 KRT18 TFCP2L1 IRF6 PPL EPCAM KRT17 RAB25 EHF FLNB SHROOM3 EPHA2 CLDN1 ELF3 ITGA2 SPINT1 SPINT2 PLXNB2 VIL1 ADAM9 AKR1C3 ANXA4 PROM1 DDR1 CD24 ESRP1 TACSTD2 KRT6A DSG2 KRT23 PERP KRT7 KRT8 KRT19 JUP PKP3 |
F | 2.40E−12 | 47 | Cell motility | NTN4 ITGB8 ITGB6 LAMA5 ITGB4 CCL28 CXCL5 PLXNB1 CD151 FAM83H SEMA4B PLXNB2 LAMB3 VIL1 MMP7 ANXA3 DUOXA2 GRB7 PTPRK F11R SPINT2 ADAM9 EFNA1 ADGRG1 ITGA3 EPCAM SOX9 DAB2IP EPHA2 ITGA2 DUOX2 JUP CDH1 LAMC2 SLC12A2 RAB25 DDR1 PTPRF CXADR CLDN1 FUT3 CLDN4 SMIM22 TACSTD2 CD24 ERBB3 ATP1B1 |
F | 2.49E−12 | 61 | Anatomical structure morphogenesis | PROM1 LAMC2 NTN4 SOX9 VIL1 LAMA5 EPHA2 PLXNB1 EFNA1 CDC42EP4 SEMA4B PLXNB2 LAMB3 LIF DAB2IP ANXA3 F11R KRT19 CD151 ADGRG1 EZR DSP HNF4A KLF5 MYH14 SHB PERP TFCP2L1 ITGB6 KRT17 LDLR ITGB4 RAB25 FLNB SHROOM3 DUOX2 ST14 ELF3 ITGA2 SPINT1 SPINT2 KRT8 SPTBN2 TNFAIP2 ITGA3 MMP15 JUP PKM ITGB8 DDR1 NBEAL2 ADAM9 CLDN4 SLC12A2 TACSTD2 KRT6A ABLIM1 KRT18 IER3 GRB7 MPZL2 |
F | 5.59E−12 | 53 | Movement of cell or subcellular component | LAMC2 NTN4 ITGB8 ITGB6 MYO5C LAMA5 ITGB4 EPHA2 CCL28 CXCL5 PLXNB1 EFNA1 CD151 FAM83H SEMA4B PLXNB2 LAMB3 VIL1 MMP7 ANXA3 DUOXA2 GRB7 PTPRK F11R SPINT2 ADAM9 ADGRG1 ITGA3 MYH14 EPCAM SOX9 DAB2IP ITGA2 DUOX2 JUP CDH1 DSG2 SLC12A2 DSP RAB25 DDR1 PTPRF CXADR CLDN1 FUT3 CLDN4 SMIM22 TACSTD2 CD24 ERBB3 EZR ATP1B1 SPTBN2 |
F | 6.64E−12 | 49 | Locomotion | LAMC2 NTN4 ITGB8 ITGB6 LAMA5 ITGB4 EPHA2 CCL28 CXCL5 PLXNB1 EFNA1 CD151 FAM83H SEMA4B PLXNB2 LAMB3 VIL1 MMP7 ANXA3 DUOXA2 GRB7 PTPRK F11R SPINT2 ADAM9 ADGRG1 ITGA3 EPCAM SOX9 DAB2IP ITGA2 DUOX2 JUP CDH1 SLC12A2 RAB25 DDR1 PTPRF CXADR CLDN1 FUT3 CLDN4 SMIM22 TACSTD2 CD24 ERBB3 EZR ATP1B1 SPTBN2 |
F | 1.04E−11 | 36 | Regulation of cellular component movement | PLXNB1 FAM83H SEMA4B PLXNB2 VIL1 MMP7 ANXA3 DUOXA2 GRB7 CCL28 PTPRK SPINT2 ADAM9 CD151 ITGA3 EPCAM SOX9 LAMA5 DAB2IP EPHA2 ITGA2 EFNA1 ADGRG1 DUOX2 JUP CDH1 DSG2 LAMC2 DSP RAB25 CLDN1 FUT3 CLDN4 SMIM22 TACSTD2 ERBB3 |
F | 1.22E−11 | 43 | Cell migration | NTN4 ITGB8 ITGB6 LAMA5 ITGB4 CCL28 CXCL5 PLXNB1 CD151 FAM83H SEMA4B PLXNB2 LAMB3 VIL1 MMP7 ANXA3 GRB7 PTPRK F11R ADAM9 EFNA1 ADGRG1 ITGA3 SOX9 DAB2IP EPHA2 ITGA2 JUP CDH1 LAMC2 SLC12A2 RAB25 DDR1 PTPRF CXADR CLDN1 FUT3 CLDN4 SMIM22 TACSTD2 CD24 EPCAM ATP1B1 |
F | 2.73E−11 | 34 | Regulation of cell motility | PLXNB1 FAM83H SEMA4B PLXNB2 VIL1 MMP7 ANXA3 DUOXA2 GRB7 CCL28 PTPRK SPINT2 ADAM9 CD151 ITGA3 EPCAM SOX9 LAMA5 DAB2IP EPHA2 ITGA2 EFNA1 ADGRG1 DUOX2 JUP CDH1 LAMC2 RAB25 CLDN1 FUT3 CLDN4 SMIM22 TACSTD2 ERBB3 |
F | 3.44E−11 | 14 | Cornification | DSG2 DSP KRT23 KRT18 PERP PPL KRT17 KRT7 ST14 KRT8 KRT19 JUP PKP3 KRT6A |
