Figure 9 | Scientific Reports

Figure 9

From: Dihydroartemisinin-driven selective anti-lung cancer proliferation by binding to EGFR and inhibition of NRAS signaling pathway-induced DNA damage

Figure 9

The diagram of the present work. 1. NRAS signaling pathway inhibited DNA damage and thereby facilitates the proliferation of lung cancer cells. 2. DHA could bind to EGFR molecules on the lung cancer cell membranes to drive the inhibitory effect. 3. DHA-driven blockage of the EGFR-NRAS signaling pathway leads to DNA damage, suppressing the proliferation of lung cancer cells thereupon.

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