Table 1 Demographic parameters of study groups.

From: Intravenous versus oral ‘l-ornithine-l-aspartate’ in overt hepatic encephalopathy: a randomized comparative study

 

LOLA (IV) (n = 20)

LOLA (ORAL) (n = 20)

p-value (95% C.I.)

Age (years), n (%)

 25–40

4 (20%)

5 (25%)

0.356

 40–55

12 (60%)

14 (70%)

 55–70

4 (20%)

1 (5%)

Male, n (%)

19 (95%)

20 (100%)

1.00

Female, n (%)

1 (5%)

0

Alcohol consumers

15 (75%)

19 (95%)

0.182

Smoking

5 (25%)

4 (20%)

1.00

HBV

1 (5%)

2 (10%)

1.00

HCV

1 (5%)

0

1.00

Diabetes

4 (20%)

1 (5%)

0.342

HTN

4 (20%)

0

0.106

CTP class, n (%)

 A

0

0

0.715

 B

4 (20%)

6 (30%)

 C

16 (80%)

14 (70%)

MELD, n (%)

 30–39

1 (5%)

0

0.233

 20–29

16 (80%)

13 (65%)

 10–19

3 (15%)

7 (35%)

HE precipitants/possible causation, n (%)

GI bleed

2

4

0.661

Diuretics

11

9

0.752

Sepsis

2

1

1.0

Paracentesis

6

8

0.741

Biochemical parameters

 Hb (g/dl)

9.2 ± 2.2

8.79 ± 2.82

0.611

 WBC

8.23 ± 3.57

8.23 ± 4.24

1.000

 INR

2.07 ± 0.75

1.79 ± 0.57

0.190

 Urea (mg/dl)

41.65 ± 21.93

39.65 ± 19.18

0.761

 Creatinine(mg/dl)

0.88 ± 0.33

0.93 ± 0.23

0.589

 T. Bil (mg/dl)

4.79 ± 3.27

3.52 ± 2.53

0.182

 SGOT (IU/L)

106.4 ± 133.25

81.45 ± 62.89

0.454

 SGPT (IU/L)

55.2 ± 96.47

32.05 ± 15.59

0.296

 ALP (IU/L)

84.8 ± 45.96

122.05 ± 79.83

0.078

 Protein (mg/dl)

6.33 ± 1.04

6.2 ± 0.92

0.689

 Albumin (mg/dl)

2.72 ± 0.35

2.68 ± 0.5

0.744

 Sodium (meq/L)

132.15 ± 7.29

132.95 ± 4.64

0.681

 Potassium (meq/L)

3.73 ± 0.69

4.12 ± 0.5

0.048