Table 1 Baseline information of demographic and clinical characteristics of subjects in the primary cohort and the validation cohort.
Variables | The primary cohort | The validation cohort | p-Value |
|---|---|---|---|
(n = 174) | (n = 75) | ||
Age (median (IQRs)) | 61.134 (58.579, 64.411) | 55.586 (51.737, 60.864) | < 0.0001 |
BMI (median (IQRs)) | 23.931 (22.656, 25.952) | 23.225 (22.231, 25.064) | 0.094 |
Gender (n (%)) | 0.765 | ||
Female | 101 (58.05) | 42 (56.00) | |
Male | 73 (41.95) | 33 (44.00) | |
Smoking status (n (%)) | 0.324 | ||
Never | 148 (85.06) | 60 (80.00) | |
Current or past | 26 (14.94) | 15 (20.00) | |
Alcohol consumption (n (%)) | 0.324 | ||
Never | 148 (85.06) | 60 (80.00) | |
Occasional, frequent or even daily | 26 (14.94) | 15 (20.00) | |
Physical activity (n (%)) | 0.003 | ||
Physical inactivity | 76 (43.68) | 48 (64.00) | |
Regular activity | 98 (56.32) | 27 (36.00) | |
Family history of CRC in FDR (n (%)) | 0.752 | ||
No | 153 (87.93) | 67 (89.33) | |
Yes | 21 (12.07) | 8 (10.67) | |
History of chronic constipation (n (%)) | 0.465 | ||
No | 122 (70.11) | 56 (74.67) | |
Yes | 52 (29.89) | 19 (25.33) | |
History of chronic diarrhea (n (%)) | 0.924 | ||
No | 124 (71.26) | 53 (70.67) | |
Yes | 50 (28.74) | 22 (29.33) | |
History of chronic appendicitis or appendectomy (n (%)) | 0.098 | ||
No | 156 (89.66) | 72 (96.00) | |
Yes | 18 (10.34) | 3 (4.00) | |