Table 1 Baseline information of demographic and clinical characteristics of subjects in the primary cohort and the validation cohort.

From: Derivation and validation of a nomogram incorporating modifiable lifestyle factors to predict development of colorectal adenomas after negative index colonoscopy

Variables

The primary cohort

The validation cohort

p-Value

(n = 174)

(n = 75)

Age (median (IQRs))

61.134 (58.579, 64.411)

55.586 (51.737, 60.864)

< 0.0001

BMI (median (IQRs))

23.931 (22.656, 25.952)

23.225 (22.231, 25.064)

0.094

Gender (n (%))

0.765

Female

101 (58.05)

42 (56.00)

 

Male

73 (41.95)

33 (44.00)

 

Smoking status (n (%))

0.324

Never

148 (85.06)

60 (80.00)

 

Current or past

26 (14.94)

15 (20.00)

 

Alcohol consumption (n (%))

0.324

Never

148 (85.06)

60 (80.00)

 

Occasional, frequent or even daily

26 (14.94)

15 (20.00)

 

Physical activity (n (%))

0.003

Physical inactivity

76 (43.68)

48 (64.00)

 

Regular activity

98 (56.32)

27 (36.00)

 

Family history of CRC in FDR (n (%))

0.752

No

153 (87.93)

67 (89.33)

 

Yes

21 (12.07)

8 (10.67)

 

History of chronic constipation (n (%))

0.465

No

122 (70.11)

56 (74.67)

 

Yes

52 (29.89)

19 (25.33)

 

History of chronic diarrhea (n (%))

0.924

No

124 (71.26)

53 (70.67)

 

Yes

50 (28.74)

22 (29.33)

 

History of chronic appendicitis or appendectomy (n (%))

0.098

No

156 (89.66)

72 (96.00)

 

Yes

18 (10.34)

3 (4.00)

 
  1. Continuous variables were compared using the Wilcoxon–Mann–Whitney test. Categorical variables were compared using the Pearson Chi-square test. All tests were two-sided.
  2. IQR interquartile range, BMI body mass index, CRC colorectal cancer, FDR first-degree relative.