Table 3 Variable selection through the univariate/multivariate Cox-PH regression analysis for predicting risks of colorectal adenoma occurrence based on the primary cohort.
Variables | The univariate Cox-PH regression analysis | Variables | The multivariate Cox-PH regression analysis | |||
|---|---|---|---|---|---|---|
HR (95% CI) | p-Value | HRa (95% CI) | p-Value | VIF | ||
Age | 1.099 (1.048–1.153) | 0.001 | Age | 1.102 (1.047–1.161) | < 0.0001 | 1.040 |
BMI | 1.147 (1.038–1.269) | 0.007 | BMI | 1.133 (1.031–1.246) | 0.010 | 1.003 |
Gender | 0.025 | Gender | 0.272 | |||
Female | Reference | Female | Reference | Reference | ||
Male | 1.743 (1.073–2.832) | Male | 1.325 (0.802–2.189) | 1.043 | ||
Smoking status | 0.197 | Smoking status | – | |||
Never | Reference | Never | – | – | ||
Current or past | 1.481 (0.816–2.691) | Current or past | – | – | ||
Alcohol consumption | 0.077 | Alcohol consumption | – | |||
Never | Reference | Never | – | – | ||
Occasional, frequent or even daily | 1.683 (0.945–3.000) | Occasional, frequent or even daily | – | – | ||
Physical activity | 0.438 | Physical activity | – | |||
Physical inactivity | Reference | Physical inactivity | – | – | ||
Regular activity | 0.822 (0.500–1.349) | Regular activity | – | – | ||
Family history of CRC in FDR | 0.255 | Family history of CRC in FDR | – | |||
No | Reference | No | – | – | ||
Yes | 1.590 (0.716–3.529) | Yes | – | – | ||
History of chronic constipation | 0.495 | History of chronic constipation | – | |||
No | Reference | No | – | – | ||
Yes | 1.203 (0.707–2.047) | Yes | – | – | ||
History of chronic diarrhea | 0.586 | History of chronic diarrhea | – | |||
No | Reference | No | – | – | ||
Yes | 0.861 (0.502–1.477) | Yes | – | – | ||
History of chronic appendicitis or appendectomy | 0.704 | History of chronic appendicitis or appendectomy | – | |||
No | Reference | No | – | – | ||
Yes | 1.179 (0.504–2.759) | Yes | – | – | ||
