Table 3 Relative gene expression (Average ΔCt) and axis fold change (AFC) in gene expression at baseline with respect to controls and post-yoga levels with respect to pre-yoga levels in RPL and RIF patients.

From: Yoga and its effect on sperm genomic integrity, gene expression, telomere length and perceived quality of life in early pregnancy loss

GOI

Control

RPL

RIF

ΔCt Controls

ΔCt Pre- Yoga

ΔCt Post- Yoga

p-value

r value

Axis fold change

ΔCt Pre-Yoga

ΔCt Post-Yoga

p-value

r value

Axis fold change

Baseline

Post-yoga

Baseline

Post-yoga

FOXG1

3.8 ± 1.17

4.19 ± 1.17

3.65 ± 0.82

0.004**

0.7353

-1.09

1.21

4.6 ± 1.7

4.28 ± 1.35

0.171

0.7484

− 1.94

0.70

SOX3

1.88 ± 1.46

1.59 ± 1.58

1.45 ± 0.76

0.978

0.3901

− 1.62

0.61

3.35 ± 2.05

2.64 ± 1.32

0.0067**

0.8553

− 4.51

1.32

STAT4

8.14 ± 2.28

7.13 ± 2.4

7.32 ± 2.61

0.510

0.7279

3.26

− 0.36

7.8 ± 1.59

8.3 ± 1.32

0.127

0.5876

2.08

− 1.14

RPS6

1.92 ± 1.32

1.85 ± 1.22

1.38 ± 0.87

0.014*

0.47

3.87

− 1.49

2.7 ± 1.77

2.47 ± 1.55

0.255

0.7392

1.95

0.48

RBM9

1.15 ± 1.89

0.66 ± 0.86

0.57 ± 1.07

0.861

− 0.063

2.52

0.22

2.41 ± 1.35

1.92 ± 0.96

0.0083**

0.0108

− 4.32

0.94

RPL10A

3.54 ± 1.77

2.89 ± 1.11

3.07 ± 1.23

0.545

0.3844

1.78

− 0.54

3.64 ± 1.21

3.37 ± 0.71

0.946

0.3614

− 1.04

0.36

RPS17

1.26 ± 1.1

1.11 ± 1.34

1.04 ± 0.66

0.492

0.7073

0.38

0.37

1.53 ± 0.97

1.33 ± 081

0.151

0.2232

− 0.82

0.37

RPL29

0.77 ± 1.23

0.75 ± 1.8

0.63 ± 1.18

0.637

0.6798

-0.21

0.13

0.98 ± 0.96

0.9 ± 0.82

0.480

0.1669

− 0.45

0.21

WNT5A

2.1 ± 1.5

1.01 ± 2.15

1.24 ± 1.42

0.581

0.6894

2.93

-0.64

1.13 ± 2.13

0.82 ± 2.6

0.065

-0.207

2.33

0.86

HSP90

3.59 ± 1.58

2.28 ± 2.13

2.7 ± 1.82

0.252

0.3589

4.34

0.38

2.13 ± 2.49

2.56 ± 3.03

0.0003***

0.5839

5.73

− 1.97

TOMM7

3.56 ± 1.64

2.17 ± 2.5

2.75 ± 2.17

0.173

0.5287

4.12

− 1.88

3.06 ± 2.12

2.45 ± 2.39

0.106

0.1296

3.51

0.20

EIF5A

3.45 ± 1.32

2.99 ± 2.01

3.14 ± 1.75

0.736

0.1335

1.81

− 0.93

2.98 ± 2.53

3.11 ± 2.57

0.186

0.3376

2.54

− 1.55

OGG1

2.75 ± 2.15

1.78 ± 1.22

0.94 ± 1.98

0.073

0.262

2.52

2.7

2.97 ± 1.65

1.64 ± 2.04

0.523

0.2041

0.80

2.81

PARP1

2.4 ± 1.6

1.45 ± 1.6

0.56 ± 1.86

0.007**

0.478

2.27

2.8

2.3 ± 2.01

0.79 ± 2.09

0.945

0.2101

1.51

4.71

  1. Values expressed as mean ± sd. *p < 0.05 was considered significant. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
  2. GOI, Gene of interest; FOXG1, Forkhead box G1; SOX3, SRY (sex determining region Y)-box 3; STAT4, Signal transducer and activator of transcription 4); RPS6, Ribosomal protein S6); RBM9, RNA binding motif protein 9); RPL10A, Ribosomal protein L10A; RPS17, Ribosomal protein S17; RPL29, Ribosomal protein L29; WNT5A, Wnt Family Member 5A; HSP90, Heat shock protein 90; TOMM7, Translocase of outer mitochondrial membrane 7); EIF5A, Eukaryotic translation initiation factor 5A; OGG1, 8-oxoguanine DNA glycosylase; PARP1, Poly(ADP-ribose) polymerase 1; r, correlation coefficient.
Back to article page