Table 7 Effect of NAR and NAR-HNPs on blood glucose and serum insulin levels in experimental rats.

From: Anti-depressant effect of Naringenin-loaded hybridized nanoparticles in diabetic rats via PPARγ/NLRP3 pathway

Groups

Parameters

Blood glucose (mg/dl)

Serum insulin (mU/l)

Normal

122.33bc ± 7.56

64.30b ± 4.03

Free NAR

119.17bc ± 9.51

60.06b ± 4.35

NAR-HNPs

117.67bc ± 6.89

55.60b ± 1.53

Control STZ

588.00acd ± 9.48

37.77acd ± 5.58

STZ + unloaded HNPs

591.11acd ± 6.45

37.09 acd ± 5.15

STZ + NAR (50 mg/kg)

468.50abd ± 54.53

71.13b ± 3.59

STZ + NAR-HNPs (50 mg/kg)

253.83abc ± 53.37

70.52b ± 8.89

STZ + NAR (50 mg/kg) + GW9662

571.17acd ± 28.83

41.16acd ± 3.40

  1. Results are stated as means ± SEM (n = 6), a vs normal group, b vs control STZ group, c vs STZ + NAR (50 mg/kg), d vs STZ + NAR-HNPs (50 mg/kg) at p < 0.05. NAR, naringenin; STZ, streptozotocin; NAR-HNPs, naringenin- loaded hybridized nanoparticles.
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