Figure 6

Impact of COVID-19 booster vaccination on antibody-dependent NK cell-mediated responses against SARS-CoV-2 Wuhan-Hu-1 and Omicron XBB.1.5 spike variants in elderly nursing home residents. The frequencies of LAMP1 (lysosomal-associated membrane protein 1)-producing NK cells against Wuhan-Hu-1 and Omicron XBB.1.5 are shown in (A) and (B), respectively. The frequencies of IFN (interferon) γ-producing NK cells against Wuhan-Hu-1 and Omicron XBB.1.5 are shown in (C) and (D), respectively. The number of participants analysed at the different sampling times is shown. Bars indicate medians and IQRs. P values for differences are shown.