Table 2 Functional annotation of FMGs in ESCC.

From: A novel fatty acid metabolism-related signature identifies MUC4 as a novel therapy target for esophageal squamous cell carcinoma

Category

ID

Description

P-value

Biology process

GO:0006631

Fatty acid metabolic process

9.58E−90

GO:0001676

Long-chain fatty acid metabolic process

9.07E−46

GO:0033559

Unsaturated fatty acid metabolic process

3.46E−45

GO:0006633

Fatty acid biosynthetic process

6.71E−45

GO:0120254

Olefinic compound metabolic process

1.84E−42

GO:0072330

Monocarboxylic acid biosynthetic process

6.60E−42

GO:0005777

Peroxisome

6.32E−13

GO:0042579

Microbody

6.32E−13

GO:0005782

Peroxisomal matrix

1.54E−09

GO:0031907

Microbody lumen

1.54E−09

GO:0005759

Mitochondrial matrix

2.05E−08

GO:0031301

Integral component of organelle membrane

1.08E−05

GO:0016614

Oxidoreductase activity, acting on CH–OH group of donors

1.37E−19

GO:0016616

Oxidoreductase activity, acting on the CH–OH group of donors, NAD or NADP as acceptor

1.75E−17

GO:0016627

Oxidoreductase activity, acting on the CH–CH group of donors

2.36E−16

GO:0016705

Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

3.94E−15

GO:0005506

Iron ion binding

1.97E−13

GO:0003995

Acyl-CoA dehydrogenase activity

5.81E−13

KEGG pathway

hsa00350

Tyrosine metabolism

1.72E−08

hsa00380

Tryptophan metabolism

6.28E−08

hsa04146

Peroxisome

1.13E−07

hsa00410

Beta-alanine metabolism

1.25E−07

hsa01212

Fatty acid metabolism

7.78E−37

hsa00071

Fatty acid degradation

5.10E−31

hsa00590

Arachidonic acid metabolism

1.64E−28

hsa01040

Biosynthesis of unsaturated fatty acids

4.26E−22

hsa03320

PPAR signaling pathway

2.15E−18

hsa00280

Valine, leucine and isoleucine degradation

7.96E−16

hsa00062

Fatty acid elongation

1.56E−14

hsa00620

Pyruvate metabolism

6.07E−13

hsa04936

Alcoholic liver disease

3.84E−12

hsa00010

Glycolysis/gluconeogenesis

9.84E−10

hsa00982

Drug metabolism—cytochrome P450

2.19E−09

  1. FMGs Fatty acid metabolism-related genes.