Table 2 Functional annotation of FMGs in ESCC.
Category | ID | Description | P-value |
|---|---|---|---|
Biology process | GO:0006631 | Fatty acid metabolic process | 9.58E−90 |
GO:0001676 | Long-chain fatty acid metabolic process | 9.07E−46 | |
GO:0033559 | Unsaturated fatty acid metabolic process | 3.46E−45 | |
GO:0006633 | Fatty acid biosynthetic process | 6.71E−45 | |
GO:0120254 | Olefinic compound metabolic process | 1.84E−42 | |
GO:0072330 | Monocarboxylic acid biosynthetic process | 6.60E−42 | |
GO:0005777 | Peroxisome | 6.32E−13 | |
GO:0042579 | Microbody | 6.32E−13 | |
GO:0005782 | Peroxisomal matrix | 1.54E−09 | |
GO:0031907 | Microbody lumen | 1.54E−09 | |
GO:0005759 | Mitochondrial matrix | 2.05E−08 | |
GO:0031301 | Integral component of organelle membrane | 1.08E−05 | |
GO:0016614 | Oxidoreductase activity, acting on CH–OH group of donors | 1.37E−19 | |
GO:0016616 | Oxidoreductase activity, acting on the CH–OH group of donors, NAD or NADP as acceptor | 1.75E−17 | |
GO:0016627 | Oxidoreductase activity, acting on the CH–CH group of donors | 2.36E−16 | |
GO:0016705 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 3.94E−15 | |
GO:0005506 | Iron ion binding | 1.97E−13 | |
GO:0003995 | Acyl-CoA dehydrogenase activity | 5.81E−13 | |
KEGG pathway | hsa00350 | Tyrosine metabolism | 1.72E−08 |
hsa00380 | Tryptophan metabolism | 6.28E−08 | |
hsa04146 | Peroxisome | 1.13E−07 | |
hsa00410 | Beta-alanine metabolism | 1.25E−07 | |
hsa01212 | Fatty acid metabolism | 7.78E−37 | |
hsa00071 | Fatty acid degradation | 5.10E−31 | |
hsa00590 | Arachidonic acid metabolism | 1.64E−28 | |
hsa01040 | Biosynthesis of unsaturated fatty acids | 4.26E−22 | |
hsa03320 | PPAR signaling pathway | 2.15E−18 | |
hsa00280 | Valine, leucine and isoleucine degradation | 7.96E−16 | |
hsa00062 | Fatty acid elongation | 1.56E−14 | |
hsa00620 | Pyruvate metabolism | 6.07E−13 | |
hsa04936 | Alcoholic liver disease | 3.84E−12 | |
hsa00010 | Glycolysis/gluconeogenesis | 9.84E−10 | |
hsa00982 | Drug metabolism—cytochrome P450 | 2.19E−09 |