Figure 6 | Scientific Reports

Figure 6

From: LncRNA TUG1 mediates microglial inflammatory activation by regulating glucose metabolic reprogramming

Figure 6

TUG1 knockout alleviates the accumulation of metabolism and the blocked TCA cycle in microglia. (a) The Principal Component Analysis (PCA) of groups (n = 6). (b) The expression level of differential metabolites Citric acid of different groups (n = 6). (c) The expression level of differential metabolites Cis-Aconitic acid of different groups (n = 6). (d) The expression level of differential metabolites Succinic acid of different groups (n = 6). (e) The expression level of differential metabolites Fumaric acid of different groups (n = 6). (f) The ratio of Cis-Aconitic acid to Citric acid. (g) The ratio of Succinic acid to Citric acid. (h) The ratio of Succinic acid to Fumaric acid. (i) Heatmap of differential metabolites between the different groups (n = 6). Error bars indicate SEM. *P < 0.05, **P < 0.01.

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