Figure 1 | Scientific Reports

Figure 1

From: Genome wide association study and genomic risk prediction of age related macular degeneration in Israel

Figure 1The alternative text for this image may have been generated using AI.

Prediction accuracy of selected PRS models. We show the ROC curve for the following AMD prediction models: the top C + T PRS (Fig. S3) + covariates (age, sex, PC1, and PC2); the top LDpred2 PRS + covariates; and a covariates-only model. The C + T PRS parameters were r2 > 0.5 and P < 5 × 10−8, and the LDpred2 PRS parameters were P = 0.056 and sparse = TRUE. The AUC estimates (after cross-validation) are indicated on top of the plot.

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