Table 5 The physiochemical properties and solubility of different drugs.
From: Solubility of lumiracoxib in supercritical carbon dioxide
Drug | Mw (g·mol−1) | Molecular Formula | Molecular structure | Pressure (bar) | Temperature (K) | Solubility (mole fraction) | Ref |
|---|---|---|---|---|---|---|---|
Lumiracoxib | 293.72 | C15H13ClFNO2 |
| 120–400 | 308–338 | 4.74 × 10–5-3.46 × 10–4 | Current investigation |
Triamcinolone Acetonide | 434.5 | C24H31FO6 |
| 120–270 | 308–338 | 6.90 × 10−6 to 2.13 × 10−4 | |
Imatinib mesylate | 589.71 | C30H35N7O4S |
| 120–270 | 308–338 | 4.8610–7 to .4.0610–6 | |
Aprepitant | 534.435 | C23H21F7N4O3 |
| 120–330 | 308–338 | 0.45 × 10−5–7.67 × 10−5 | |
Amiodarone hydrochloride | 681.77 | C25H30ClI2NO3 |
| 120–270 | 308–343 | 2.510 × 10−5 to 1.012 × 10−3 | |
Loratadine | 382.89 | C22H23ClN2O2 |
| 120–270 | 308–338 | 0.45 × 10−5 to 1.3016 × 10−3 | |
Ketotifen fumarate | 425.5 | C23H23NO5S |
| 120–300 | 308–338 | 0.211 × 10−4 to 10.766 × 10−4 | |
Esomeprazole | 345.42 | C17H19N3O3S |
| 120–270 | 308–338 | 1.11 × 10−5 to 9.10 × 10−4 | |
Azathioprine | 277.26 | C9H7N7O2S |
| 120–270 | 308–338 | 0.27 × 10−5 to 1.83 × 10−5 | |
Lansoprazole | 369.36 | C16H14F3N3O2S |
| 120–270 | 308–338 | 1.15 × 10−5 to 7.36 × 10−4 | |
Sunitinib malate | 532.5612 | C26H33FN4O7 |
| 120–270 | 308–338 | 0.5 × 10−5 to 8.56 × 10−5 |
