Table 3 Mutations in the coding region of SQLE gene with amino acid substitutions.
Dermatophytes | ITS accession no | Nucleotide substitution | SQLE protein accession no. | Missense mutations in SQLE | MIC (mg/L) |
|---|---|---|---|---|---|
T. indotineae | OR230111 | T1189C | WNA16467 | Phe397Leu | 4 |
T. indotineae | OR230115 | T1189C, T931C | WNA16469 | Phe397Leu, Phe311Leu | 4 |
T. indotineae | OR230117 | T1189C | WNA16471 | Phe397Leu | 2 |
T. mentagrophytes XVII | OR230122 | G828C, T1189C | WNA16472 | Lys276Asn, Phe397Leu | 4 |
T. mentagrophytes XVII | OR230124 | G828C, T1189C | WNA16473 | Lys276Asn, Phe397Leu | 4 |
T. indotineae | OR230112 | No substitution | WNA16468 | No mutation | 0.5 |
T. indotineae | OR230118 | No substitution | WNA16470 | No mutation | 0.5 |
T. mentagrophytes XVII | OR230126 | G828C, C1255T | WNA16474 | Lys276Asn, Leu419Phe, | 0.5 |
