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Figure 1

From: Stochastic journeys of cell progenies through compartments and the role of self-renewal, symmetric and asymmetric division

Figure 1

General stochastic model of cell division, death and differentiation for an ordered sequence of compartments. Grey cells represent a death event. Self-renewal events take place with rate \(\lambda_i\), symmetric division events with rate \(s_i\), and asymmetric division events with rate \(a_i\). Differentiation events happen with per-cell rate \(\nu_i\) (forward) or \(\xi_i\) (backward). Death events have per-cell rate \(\mu_i\). Each per-cell rate is a real positive number.

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