Table 2 Descriptive characteristics of the participants.
From: Brain network topology and its cognitive impact in adult glioma survivors
Characteristics | Patients (n = 50) | Controls (n = 50) |
|---|---|---|
Demographics | ||
Age (in years) | ||
Mean (SD) | 42.58 (13) | 42.42 (13) |
Median (range) | 39 (23–70) | 40 (21–72) |
Sex: females, n (%) | 25 (50) | 25 (50) |
Education (Verhage categories)66 | ||
Level 3, n (%) | 1 (2) | 1 (2) |
Level 4, n (%) | 8 (16) | 8 (16) |
Level 5, n (%) | 8 (16) | 8 (16) |
Level 6, n (%) | 16 (32) | 16 (32) |
Level 7, n (%) | 17 (34) | 17 (34) |
Handedness | ||
Right, n (%) | 42 (84) | 47 (94) |
Left, n (%) | 5 (10) | 3 (6) |
Both, n (%) | 3 (6) | 0 (0) |
Anti-epileptic drugs usage | ||
Yes, n (%) | 33 (66) | 0 (0) |
Tumor treatment | ||
Time since last treatment in years, mean (SD) | 5 (3,5) | |
Surgery, n (%) | 43 (86) | |
Radiotherapy, n (%) | 38 (76) | |
Total dose | ||
54 Gy, n (%) | 20 (53) | |
59.4 Gy, n (%) | 7(18) | |
60 Gy, n (%) | 11 (29) | |
Chemotherapy, n (%) | 35 (70) | |
PCV, n (%) | 23 (46) | |
TMZ, n (%) | 12 (24) | |
Tumor location* | ||
Frontal, n (%) | 35 (70) | |
Parietal, n (%) | 6 (12) | |
Temporal, n (%) | 15 (30) | |
Occipital, n (%) | 1 (2) | |
Brainstem, n (%) | 2 (4) | |
Thalamus, n (%) | 1 (2) | |
Involved hemisphere | ||
Left, n (%) | 31 (62) | |
Right, n (%) | 18 (36) | |
Both, n (%) | 1 (2) | |
Lesion volume (cm3) | ||
Median (range) | 52.24 (1.87–162.19) | |
Tumor characteristics | ||
Histology (WHO 2016) | ||
Oligodendroglioma, n (%) | 30 (60) | |
Diffuse astrocytoma, n (%) | 16 (22) | |
Anaplastic astrocytoma, n (%) | 2 (4) | |
Anaplastic oligodendroglioma, n (%) | 2 (4) | |
WHO grade | ||
2, n (%) | 27 (54) | |
3, n (%) | 23 (46) | |
IDH mutation | ||
IDH1-mutation, n (%) | 24 (48) | |
IDH1- wild type, n (%) | 5 (10) | |
IDH1, NOS, n (%) | 21 (42) | |
