Figure 2

Consensus clustering analysis was performed for UC patients. The expression of GLS was examined in GSE92415 (A) and GSE87473 (K); (B) Schematic diagram of GLS protein interactions; Consensus clustering matrix for the two UC subtypes in GSE92415 (C), GSE87473 (L), and GSE72514 (R); The CDF curves from k = 2 to 10 in GSE92415 (D), GSE87473 (M), and GSE72514 (S). The relative change in area under cumulative distribution function (CDF) curve from k = 2–10 in GSE92415 (E), GSE87473 (N), and GSE72514 (T); PCA distribution plot for the UC subtype in GSE92415 (F), GSE87473 (O), and GSE72514 (U); t-SNE plot of Cluster1 and Cluster2 in GSE92415 (G), GSE87473 (P), and GSE72514 (V); (H) Relationship between subclusters and age in GSE92415; (I) Relationship between subclusters and mayo score in GSE92415; (J) Relationship between subclusters and placebo or golimumab 6-week response in GSE92415; (Q) Relationship between subclusters and disease extent in GSE87473.