Table 1 Summary of average number of mutations.
WGS | WES | ||||||||
|---|---|---|---|---|---|---|---|---|---|
DOX (n = 3) | GEM (n = 3) | PTX (n = 4) | TPT (n = 3) | TPT (n = 3) | DOX (n = 3) | ETP (n = 3) | GEM (n = 3) | PTX (n = 3) | |
Indels | |||||||||
Disruptive inframe ins | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 1.00 | 0.00 | 0.00 | 0.00 |
Frameshift | 0.00 | 1.00 | 1.33 | 2.33 | 0.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Frameshift plus stop-gained | 0.00 | 0.00 | 0.00 | 0.33 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 |
Inframe insertion | 0.00 | 0.00 | 1.00 | 0.33 | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 |
Intergenic | 27.67 | 43.00 | 26.75 | 24.67 | 47.67 | 2.00 | 3.50 | 1.00 | 1.00 |
Intragenic | 10.00 | 5.67 | 9.00 | 9.00 | 14.33 | 1.00 | 2.00 | 1.00 | 1.00 |
Intron | 12.00 | 20.33 | 16.25 | 15.67 | 32.33 | 1.00 | 1.00 | 4.00 | 1.50 |
Splice region plus intron | 0.00 | 0.00 | 0.00 | 103.3 | 0.00 | 0.00 | 0.00 | 1.00 | 0.00 |
SNVs | |||||||||
Disruptive inframe del | 0.00 | 1.00 | 1.00 | 0.67 | 0.00 | 1.00 | 0.00 | 1.00 | 1.33 |
Frameshift | 1.00 | 2.00 | 1.00 | 22.33 | 2.00 | 3.00 | 1.67 | 1.00 | 3.00 |
Inframe deletion | 0.00 | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 2.00 | 0.00 | 0.00 |
Intergenic | 898.33 | 1303.3 | 1416.6 | 258.67 | 2635.7 | 25.00 | 19.00 | 17.00 | 21.33 |
Intragenic | 272.00 | 403.33 | 389.25 | 77.67 | 834.67 | 15.33 | 12.33 | 10.33 | 11.33 |
Intron | 448.67 | 701.33 | 764.00 | 128.3 | 1358.33 | 28.00 | 27.00 | 33.00 | 22.67 |
Missense | 16.00 | 14.00 | 12.75 | 7.00 | 34.33 | 15.00 | 19.67 | 21.67 | 15.67 |
Others | 1.00 | 1.00 | 0.00 | 0.00 | 1.33 | 1.00 | 1.00 | 1.50 | 1.00 |
Splice region plus intron | 1.00 | 1.67 | 2.00 | 30.00 | 3.33 | 1.67 | 1.50 | 1.00 | 1.33 |
Start lost | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 | 1.00 |
Stop gained | 0.00 | 2.50 | 1.00 | 0.00 | 1.67 | 1.50 | 2.00 | 2.67 | 0.00 |
Stop lost | 0.00 | 1.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
Synonymous | 3.00 | 7.33 | 4.00 | 6.33 | 7.67 | 6.67 | 5.33 | 7.67 | 5.33 |
