Figure 1

MARK4 was upregulated in vitro and in vivo. (A, B) The expression of the MARK4 protein in STZ-induced diabetic cardiomyopathy mice (n = 6 samples per group). (C) The effects of different durations of high-glucose and high-lipid treatment on cardiomyocyte viability (n = 4 samples per group). (D, E) The expression of the MARK4 protein in cardiomyocytes treated with high-glucose and high-lipid (n = 6 samples per group). The data are presented as the means ± SDs. Significant differences are indicated by *P < 0.05, **P < 0.01, and ***P < 0.001.