Figure 8 | Scientific Reports

Figure 8

From: MARK4 aggravates cardiac dysfunction in mice with STZ-induced diabetic cardiomyopathy by regulating ACSL4-mediated myocardial lipid metabolism

Figure 8

Relationships between MARK4 and ACSL4 and lipid metabolism. (A–F) Western blot and quantitative analysis of the levels of MARK4, ACSL4, CPT1A, CPT2, and PPAR-α (n = 6 samples per group). (G) Changes in the mitochondrial membrane potential in each group (n = 3 samples per group). (H, I) Changes in reactive oxygen species levels in each group (n = 3 samples per group). The data are presented as the means ± SDs. Significant differences are indicated by *P < 0.05, **P < 0.01, and ***P < 0.001.

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