Table 1 Effect of MARK4 knockdown on cardiac function in STZ-induced DCM mice (means ± SDs, n = 8).

From: MARK4 aggravates cardiac dysfunction in mice with STZ-induced diabetic cardiomyopathy by regulating ACSL4-mediated myocardial lipid metabolism

Groups

LVEF(%)

LVFS(%)

LVIDd(cm)

LVIDs(cm)

Con

84.65 ± 3.79

47.61 ± 4.37

0.25 ± 0.03

0.13 ± 0.02

Mod

74.5 ± 2.72***

37.49 ± 2.35***

0.27 ± 0.02

0.17 ± 0.02**

Mod + AAV9-shMARK4

80.23 ± 4.08##

42.71 ± 3.91*#

0.24 ± 0.02

0.14 ± 0.02##

Mod + AAV9-shNC

75.68 ± 1.99***

38.44 ± 1.75***

0.26 ± 0.03

0.16 ± 0.02*

  1. *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the control group; #P < 0.05 and ##P < 0.01 compared with the model group.
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