Figure 6 | Scientific Reports

Figure 6

From: Adolescent alcohol exposure persistently alters orbitofrontal cortical encoding of Pavlovian conditional stimulus components in female rats

Figure 6

No AIE effect was observed on NAc phasic activity after CS onset, CS offset, or the first receptacle entry after CS offset. Phasic activity in NAc neurons was analyzed during PCA baseline and omission sessions. Firing activity for neurons that showed phasic excitatory activity (in green) and phasic inhibitory activity (in blue) are shown in each figure for CON (left graphs) and AIE (right graphs). The red box represents the 2-s baseline window for the phasic activity analysis. The thickness of each line reflects the proportion of neurons exhibiting phasic excitation or inhibition (non-phasic cells are not shown). Inset: box plots show the amplitude of excitation during the target window (blue box) for each phasic excitatory cell. NAc phasic activity during the baseline session (A, B, and C) and omission session (D, E, and F) are presented for CS onset, CS offset, and the first receptacle entry (RE) after CS offset, respectively. No AIE effect was observed during these events on the amplitude of the activity displayed by phasic excitatory cells during both recording sessions. Neuronal phasic activity data are presented as mean firing rate. Box plots showed the median, interquartile range, and minimum and maximum data values, with CON in gray and AIE in orange. Note that the percentage of neurons displaying phasic activity are descriptive results. For statistical details of the analyses on the amplitude of phasic excitatory cells activity, see Supplemental Table S2.

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