Table 1 Demographic and clinical characteristics of the ACS patients and CG individuals.

From: IL10 promoter variants are associated with gene expression but they are not markers of susceptibility to acute coronary syndrome

Demographic characteristic

CG, n (%)

ACS group, n (%)

p

Cardiovascular risk factor

 Age (median, IQR)

57 (51–63)

64 (57–70)

 < 0.0001

 Male

143 (48)

215 (72)

 < 0.0001

 Female

157 (52)

85 (28)

 < 0.0001

 High blood pressure

100 (33)

214 (71)

 < 0.0001

 Dyslipidemia

65 (22)

148 (49)

 < 0.0001

 T2DM

65 (22)

172 (57)

 < 0.0001

 Smoking

66 (22)

143 (48)

 < 0.0001

 Overweight

85 (28)

116 (39)

0.0043

 Obesity

81 (18)

80 (27)

0.0084

 Sedentary lifestyle

88 (29)

181 (60)

 < 0.0001

 Reinfarction

53 (18)

Medication

 ASA

3 (1)

287 (96)

 < 0.0001

 Clopidogrel

(92)

 Metformin

18 (6)

21 (7)

0.6196

 Insulin

12 (4)

 Antihypertensive

11 (4)

61 (20)

 < 0.0001

 Statin

21 (3)

285 (95)

 < 0.0001

 Bezafibrate

5 (2)

8 (3)

0.6043

 Losartan

21 (7)

54 (18)

 < 0.0001

 β-blocker

6 (2)

180 (60)

 < 0.0001

 Enalapril

6 (2)

135 (45)

 < 0.0001

 Captopril

51 (17)

 Isosorbide

72 (24)

 Amlodipine

46 (12)

30 (10)

0.4341

 Heparin

42 (14)

 Enoxaparin

201 (67)

  1. Obesity and overweight were defined according to the World Health Organization criteria15.
  2. CG control group, ACS acute coronary syndrome, IQR interquartilic range, T2DM type 2 diabetes mellitus, ASA acetyl salycilc acid, and ACEI angiotensing converting enzyme inhibitors.