Figure 1 | Scientific Reports

Figure 1

From: Development of a single-chain variable antibody fragment against a conserved region of the SARS-CoV-2 spike protein

Figure 1

The GTH peptide on the SARS-CoV-2 spike protein. (a) The position of the GTH peptide in the spike proteins of the α, β, γ and o BA.5 and BQ1.1 mutant strains. The vertical blue lines show the mutation sites in the spike proteins; the purple boxes show the position of the GTH peptide. SP: signal peptide. HR1 and HR2: heptad repeat 1 and 2, respectively. TM: transmembrane domain. (b) The 3D structure showing the position of the GTH peptide on the spike protein. The GTH peptide shown in light blue is located in the S2 structural domain and on the surface of the spike protein. The illustration was modified from PDB 7DF3 at https://www.wwpdb.org/pdb?id=pdb_00007df3.

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